93例小气道功能异常患者肺功能分析  

PULMONARY FUNCTION ANALYSIS OF 93 PATIENTS WITH SMALL AIRWAY DYSFUNCTION

作　　者：张勃[1] 张庆[1] 范金荣[1] 

机构地区：[1]承德医学院附属医院呼吸内科,河北承德067000

出　　处：《承德医学院学报》2012年第2期134-136,共3页Journal of Chengde Medical University

摘　　要：目的:探讨单纯胸闷气短患者肺功能小气道指标25%用力呼气流速(FEF25)、最大中期呼气流速(FEF25-75)、75%用力呼气流速(FEF75)的变化及临床意义。方法:对以胸闷气短为主诉但诊断不明确的患者(小气道功能异常组)行肺功能检测,以同期轻度阻塞性通气功能障碍的哮喘患者(哮喘组)和慢性阻塞性肺疾病(COPD)患者(COPD组)作为对照组。分别检测三组患者的小气道指标FEF25、FEF25-75、FEF75和Raw。结果:FEF25、FEF25-75和FEF75三个指标中,FEF25-75诊断小气道功能异常的灵敏度最高;小气道功能异常组FEF25、FEF25-75明显高于哮喘组和COPD组,Raw明显低于哮喘组和COPD组,差异具有统计学意义(P<0.01)。结论:FEF25-75对诊断伴有小气道功能异常的单纯胸闷气短具有临床意义,部分胸闷气短症状可能是哮喘或COPD的前奏。Objective：To investigate the clinical significances of FEF25,FEF25-75 and FEF75 in patients with simple dyspnea.Methods：The patients with simple dyspnea（small airway dysfunction group） but diagnosis is not clear were detected the indexes of pulmonary function,such as FEF25,FEF25-75,FEF75 and Raw.At the same time,asthma patients（asthma group） and COPD patients（COPD group） with mild obstructive ventilation function disability were taken as control.Results：The sensitivity of FEF25-75 was the highest to diagnose small airway dysfunction among FEF25,FEF25-75 and FEF75.FEF25 and FEF25-75 of patients in small airway dysfunction group were obviously higher than asthma group and COPD group;while the Raw was obviously lower（P0.01）.Conclusions：FEF25-75 is an important index to diagnose dyspnea with small airway dysfunction.Part of the dyspnea may be the prelude of asthma and COPD.

关 键 词：胸闷气短 小气道功能 FEF25 FEF25-75 FEF75 

分 类 号：R563[医药卫生—呼吸系统]