基于胆固醇的有机超分子智能凝胶  

Supramolecular Smart Organogel Based on Cholesterol

作　　者：孔丽[1] 孙涛[1] 张峰[1] 辛飞飞[1] 郝爱友[1] 

机构地区：[1]山东大学化学与化工学院,济南250100

出　　处：《化学进展》2012年第5期790-800,共11页Progress in Chemistry

摘　　要：胆固醇分子具有特色的多环、多手性碳结构,因此可用于构筑有机超分子凝胶智能材料。该凝胶体系除了对温度有良好的感知响应性外,对其他的外界刺激,如光、pH、超声等也能够感知并响应。由于胆固醇分子是生命体中普遍存在的生物分子,基于胆固醇的有机超分子智能凝胶在生命现象模拟、药物输运等方面具有天然的优势。本文先根据胆固醇凝胶体系的不同种类,包括光响应型、氧化还原响应型、酸碱响应型、超声响应型,金属离子响应型以及触变响应型等,对该体系的结构与性能进行了介绍,然后介绍了对凝胶因子的修饰方法,最后结合目前的研究现状,探讨了胆固醇有机超分子凝胶的应用方向及前景。Supramolecular smart organogels based on cholesterol,which has special multi-rings and multi-chiral carbon structures,have been paid much attention during recent years.This kind of gels can exhibit a dramatic change in their properties in response to temperature,as well as other environmental stimulus,such as light,pH and ultrasound.Since cholesterol molecules are the universal class of biological molecules in life,the smart cholesterol-gel materials have potential advantages in life phenomena simulation,drug delivery,etc.In the paper,the structures and properties of the gel system are introduced according to the types of the gel system at first,including photo-responsive,redox-responsive,pH-responsive,ultrasound-responsive,metal ion-responsive and thixotropy-responsive.Then the modification method of the gelator is described.Finally,based on the current developments of the system,the directions and the prospects are pointed out.

关 键 词：胆固醇 刺激响应 超分子 智能凝胶 

分 类 号：O629.21[理学—有机化学] O641.3[理学—化学]