良性前列腺增生症与代谢综合征的相关性研究  

Correlation between Benign Prostatic Hyperplasia and Metabolic Syndrome

作　　者：林秀芳[1] 杨茗[1] 董碧蓉[1] 

机构地区：[1]四川大学华西医院老年干部科,成都610041

出　　处：《中国循证医学杂志》2012年第5期524-526,共3页Chinese Journal of Evidence-based Medicine

摘　　要：目的探讨良性前列腺增生症(benign prostatic hyperplasia,BPH)与代谢综合征(metabolic syndrome,MS)的相关性。方法选择2010年5月在四川大学华西医院体检中心体检的老年男性共666例,进行MS及BPH相关指标的检查,分析比较BPH综合定义、下尿路症状、前列腺体积与MS及其组分(CDS2007标准)的相关性。结果高血压与BPH诊断有明显相关性[OR=1.309,95%CI(1.033,1.661)],低HDL-C血症(HDL-C<1.04 mmol/L)是IPSS评分异常的危险因素[OR=1.573,95%CI(1.330,1.997)],前列腺体积与肥胖、高血压、低HDL-C血症及MS呈正相关(P均<0.05)。结论 MS及其组分对BPH的影响主要体现在前列腺体积的变化,而对下尿路症状的影响相对较小。Objective To evaluate the correlation between benign prostatic hyperplasia（BPH） and metabolic syndrome（MS）.Methods Total 666 elderly male patients admitted to West China Hospital for routine physical examination in May,2010 were included in this study.The related laboratory tests of BPH and MS were taken.The correlation among BPH,lower urinary tract Symptoms（LUTS）,prostate volume（PV）,MS and its component diseases were analyzed.Results Hypertension was an important risk factor for BPH（OR=1.309,95%CI 1.033 to 1.661）,low HDL-C hyperlipidemia was a risk factor for IPSS scored over 7 points（OR=1.573,95%CI 0.330 to 0.997）,and the score of PV was positively correlated to obesity,hypertension,low HDL-C hyperlipidemia and MS（all P〈0.05）.Conclusion For the patient with BPH,MS and its component diseases mainly exert their effects on PV changes rather than LUTS.

关 键 词：良性前列腺增生症 代谢综合征 相关性 

分 类 号：R697.3[医药卫生—泌尿科学] R589[医药卫生—外科学]