盐酸纳洛酮在乙醇或阿片类中毒中的应用  

APPLICATION OF NALOXONE HCL IN TREATMENT OF ALCOHOLIC AND OPIATE POISONING

作　　者：韩爱玲[1] 袁剑萍 

机构地区：[1]河南医科大学第一附属医院急诊科,郑州450052 [2]河南漯河市科学技术协会,漯河市462000

出　　处：《中国新药杂志》2000年第5期332-333,共2页Chinese Journal of New Drugs

摘　　要：目的 :研讨盐酸纳洛酮在内科急诊中的应用。方法 :根据病情轻、中、重程度 ,首次分别静注纳洛酮0 .4,0 .8,1.2mg ,0 .5 ,1.0h后可重复应用 ,直到取得满意疗效。结果 :所治疗的病例疗效满意 ,该药除使个别患者血压升高外 ,无其他不良反应。结论 :纳洛酮是内科急症急救中安全、有效、应用范围较广的药物 。OBJECTIVE:To discuss the uses of naloxone HCl in emergent medical cases.METHODS: In alcoholic or opiate poisoning,the patient was initially treated with naloxone HCl infusion in a dose of 0.4 mg,0.8 mg,or 1.2 mg according to the severity of the poisoning. The treatment may be repeated after 0.5h or 1 h of the previous dose until satisfactory remission was obtained.RESULTS:Alcoholic or opiate poisoning can be satisfactorily relieved by naloxone HCl therapy without obvious side effects except increase in blood pressure.CONCLUSION: Naloxone HCl is a safe,effective,and widely usable agent in treatment of acute poisoning.

关 键 词：盐酸纳洛酮 阿片类中毒 Β-内啡呔 醇中毒 治疗 

分 类 号：R595.505[医药卫生—内科学] R595.606[医药卫生—临床医学]