应用国产CL-V型双叶瓣行瓣膜置换21例分析  

China-made CL-V bileaflet mechanical heart valve: a clinical application of 21 cases

作　　者：宋兵[1] 祁亮[1] 唐汉博[1] 赵宏林[1] 李元敏[1] 任旭东[1] 刘瑞生[1] 

机构地区：[1]兰州大学第一医院心血管外科,兰州730000

出　　处：《第二军医大学学报》2012年第5期567-569,共3页Academic Journal of Second Military Medical University

摘　　要：目的观察和评价新型国产CL-V型双叶型人工机械心脏瓣膜的早期临床疗效和近期随访结果。方法本组21例患者,行左房室瓣置换18例,左房室瓣及主动脉瓣联合置换3例。共植入进口瓣膜(23A)1枚,CL-V型双叶瓣23枚,其中CL-V型双叶瓣左房室瓣位21枚(25M 1枚、27M 20枚)、主动脉瓣位2枚(23A 1枚、25A 1枚)。比较术前与术后1周、术后6个月心脏房室大小、心功能、血流动力学及血液相容性指标;观察围术期及随访中是否有瓣膜相关并发症。结果随访率100%,随访时间6～61个月,平均随访时间19.8个月(1.7年)。本组无早期死亡(术后30 d内),术后早期及近期随访中血流动力学性能稳定,血液相容性良好,未发现与瓣膜有关的并发症发生。结论 CL-V型双叶瓣的早期临床疗效满意,术后近期随访中未发现人工心脏瓣膜相关的并发症,远期疗效需进一步观察研究。Objective To introduce a new type of China-made bileaflet mechanical prosthetic heart valve（CL-V bileaflet valve）and evaluate its early clinical effectiveness and short-term follow-up outcomes.Methods Twenty-one patients were included in the present study,with 18 receiving mitral valve replacement and 3 receiving combined mitral and aortic replacement.One AST bileaflet valve（imported） and 23 CL-V bileaflet valves were implanted（21 in mitral position,including one 25M and 20 27M;and 2 in aortic position,including one 23A and one 25A）.The ventricular and atrial volume,cardiac function,hemodynamics and hemocompatibility were compared before and one week,6 months after operation.Valve-related complications were observed during perioperative period and follow-up.Results All the patients were followed up for 6-61 months,with a mean of 19.8 months.There was no early mortality（ 30 d after operation）.The patients had stable hemodynamics and satisfactory hemocompatibility early after operation and during short-term follow-up;there were no valve-related complications.Conclusion The early clinical results and short-term follow-up outcomes of CL-V bileaflet prosthetic valve are satisfactory,with no valve-related complications.The long-term outcome of CL-V bileaflet prosthetic valve needs to be further observed.

关 键 词：心脏瓣膜疾病 人工心脏瓣膜 国产CL-V型双叶瓣 

分 类 号：R654.27[医药卫生—外科学]