强度不同的间歇跑台训练对生长期大鼠骨代谢及相关激素的影响  

Different strength intermittent treadmill training of growth period rats and related bone metabolism of the hormone influence

作　　者：谢顺成[1] 马学军[1] 郭成吉[1] 刘洪珍[1] 

机构地区：[1]曲阜师范大学体育科学学院,山东曲阜273165

出　　处：《中国应用生理学杂志》2012年第3期271-274,共4页Chinese Journal of Applied Physiology

基　　金：山东省科技攻关计划项目(032050117)

摘　　要：目的:探讨强度不同的间歇跑台训练对生长期大鼠骨代谢的影响,以期为青少年训练强度的制定提供理论支持。方法:选取4周龄雄性wistar大鼠70只,根据体重随机搭配分成7组(n=10):即对照组和运动组。运动组按照大鼠摄氧量分为:65%组,70%组,75%组,80%组,85%组和90%组。跑台训练9周,每周训练6 d,每组训练分3次,每次不低于10 min,中间间隔30 min。最后一次运动后24 h,取股骨和血进行骨密度(BMD)、骨量(BMC)和血清中的碱性磷酸酶(AKP),抗酒石酸酸性磷酸酶(Str-ACP)的测定。结果:①70%组股骨的BMD(0.1393±0.0031)、BMC(0.4525±0.0335)显著高于对照组(BMD:0.1200±0.0095,BMC:0.3238±0.0485)和其他各运动组(65%组BMD:0.1339±0.0062、BMC:0.4058±0.0492,75%组BMD:0.1296±0.0015、BMC:0.3869±0.0254,80%组BMD:0.1223±0.0082、BMC:0.3454±0.0483,85%组BMD:0.1250±0.0044、BMC:0.3731±0.0381,90%组BMD:0.1171±0.0047、BMC:0.3051±0.0286)(P<0.05),90%组的BMD、BMC低于对照组但未达到显著水平,其他各运动组均高于对照组;②各运动组血清AKP均显著高于对照组,其中65%组(41.015±2.114)、70%组(46.035±2.611)、75%组(43.834±3.155)、80%组(38.043±4.073)血清AKP非常显著高于对照组(26.875±1.188)(P<0.01),70%组和75%组血清AKP显著高于80%组、85%组、90%组(P<0.05),同时70%组血清AKP显著高于65%组(P<0.05),这说明70%VO2max的训练强度成骨细胞最活跃。各运动组血清StrACP均显著高于对照组,随着训练强度的增加,血清StrACP水平呈上升趋势,80%组(22.430±1.591)、85%组(23.990±1.870)、90%组(28.009±1.839)血清StrACP显著高于65%组(18.503±2.429)、70%组(16.447±2.120)和75%组(17.769±1.642)(P<0.05),90%组血清StrACP均显著高于80%组和85%组(P<0.05)。结论:70%VO2max的中等强度间歇跑台训练使生长期大鼠骨量、骨密度增加最明显。Objective： To explore the influence of different strength intermittent treadmill training of growth period rats on the bone metabolism, so as to provide the training intensity of teenagers to set theory support. Methods： Select 70 male four weeks Wistar rats according to body weight randomly divided into seven groups （ n = 10） ： the control group and the exercise group. According to the VO2max the exercise group was divided into 6 groups： 65% ,70% ,75% ,80%, 85% and 90% group. Nine weeks treadmill training, training six days a week, each group of training three times, each time not less than 10min, the interval was 30 min. The last movement after 24 h, took the femur and blood to measured the bone mineral density（BMD）, bone mass（BMC） and alkaline phosphatase （AKP）, resist tartaric acid acidic phosphatase （ Str-ACP）. Results： （±）The femoral BMD（O. 1393 --- 0.0031 ）, BMC （ O. 4525 ± 0. 0335） of 70 % group were significantly higher than those in the control group（BMD：O. 1200 ± 0.0095, BMC： 0.3238 ± 0.0485） and the other sports group（65% BMD：O. 1339 ± O.0062,BMC： 0.4058 ± 0.0492, 75% BMD： 0. 1296 ± 0.0015,BMC： 0.3869 ± 0.02.±54, 80% BMD： O. 1223 ± 0.0082,BMC： 0.3454 ± 0.0483, 85% BMD： O. 1250 ± O.0044,BMC： O. 3731 ± 0.0381, 90% BMD： O. 1171 -± 0.0047,BMC： 0. 3051 ± 0.0286） （ P 〈 0.05）, the femoral BMD, BMC of 90% group were lower than those of the control group, the other in the exercise group were higher than those in the control group; （±）Sertan AKP in the exercise group were significantly higher than those in the control group, the group of 65 % （41. 015 ± 2.114）, 70 % （46. 035 ± 2.611）, 75 % （43. 834 ± 3. 155）, and 80 % （38. 043 ± 4. 073） were very significantly higher than those in the control group （26. 875 ± 1. 188） （P 〈 0.01） ; 70% group and 75% group were significantly higher than those in the 80% group, 85% group and 90% group, while 70% group serum AKP level were significantly

关 键 词：间歇跑台训练 骨量 骨密度 

分 类 号：G80-3[文化科学—运动人体科学]