禁食、轮替疗法配合药物治疗食物不耐受的慢性荨麻疹的疗效观察  

Clinical observations on the chronic urticaria with food specific IgG positive treatment by fasting and spell

作　　者：杨啸宇[1] 邱雄[1] 金泽龙[1] 汪平[1] 牟双梦 杨闯[1] 陆小琴[1] 陈德宇[2] 

机构地区：[1]雅安职业技术学院皮肤科,四川雅安625000 [2]泸州医学院附属医院皮肤科,四川泸州646000

出　　处：《四川医学》2012年第4期584-586,共3页Sichuan Medical Journal

基　　金：四川省卫生厅科研课题(编号:090558)

摘　　要：目的旨在采用禁食、轮替疗法联合药物对食物特异性IgG阳性的慢性荨麻疹患者进行治疗,观察其疗效。方法慢性荨麻疹患者分为A、B、C 3组,A组为食物耐受组30例,采用咪唑斯叮、酮替芬治疗;B组为食物不耐受组30例,同样采用咪唑斯叮、酮替芬治疗;C组也为食物不耐受组30例,采用咪唑斯叮、酮替芬治疗同时,配合禁食轮替疗法。治疗2、6个月后观察其疗效,结果应用SPSS17.0统计软件包作统计学分析。结果治疗2个月后A组与C组的有效率相差不大,差异无统计学意义,不过均优于B组;治疗6个月后,A组与C组的有效率差异无统计学意义,但均优于B组,痊愈率也明显高于B组。结论使用禁食、轮替疗法联合药物对食物特异性IgG阳性的慢性荨麻疹患者进行治疗效果更好,值得推广。Objective To observe the effects of fasting and spell combined with antihistamines therapy on the chronic urticaria with food specific IgG positive.Methods The cases were divided into three groups,group A was 30 cases of chronic urticaria with food specific IgG negative which were treated by mizolastine and ketotifen,group B was 30 cases of chronic urticaria with food specific IgG positive which were treated the same treatment as group A,group C was 30 cases of chronic urticaria with food specific IgG positive which were treated by mizolastine and ketotifen,simultaneously fasting and spell.The effects of three groups should be observed after 2 and 6 months treatment.The data analyzed by SPSS 17.0 software.Results After two months treatment,the effective rate of the group A and C were no significant difference,but two of them were significant different from group B.After 6 months treatment,the effective rates of group A and C were no significant difference.,while the effective rates and the cure rates of group A and C were higher than group B.Conclusion The result show that the fasting and spell combined with antihistamines therapy was better for the chronic urticaria with food specific IgG positive.This treatment was worth popularizing.

关 键 词：禁食 轮替 荨麻疹 食物特异性IGG 治疗 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]