泮托拉唑对急性心肌梗死行经皮冠状动脉支架植入术患者消化道出血的预防  

Effect of pantoprazole on alimentary tract hemorrhage in patients with acute myocardial infarction performed percutaneous coronary artery stent implantation

作　　者：巩晓宏[1] 袁宇[2] 辛渭川[1] 刘超峰 

机构地区：[1]西安市中心医院心内科,陕西西安710003 [2]新乡医学院第一附属医院心内二科,河南卫辉453100 [3]陕西省中医医院,陕西西安710003

出　　处：《新乡医学院学报》2012年第5期369-371,共3页Journal of Xinxiang Medical University

摘　　要：目的观察泮托拉唑在急性心肌梗死经皮冠状动脉支架植入术(PCI)治疗中对消化道出血的预防效果。方法急性心肌梗死行PCI患者87例分为观察组45例和对照组42例,对照组给予常规治疗,观察组在常规治疗基础上加用泮托拉唑,观察2组患者住院期间PCI成功率、并发症、病死率及7 d内消化道出血发生情况。结果观察组和对照组消化道出血的发生率分别为4.4%和21.4%,观察组明显低于对照组(P<0.05)。结论急性心肌梗死PCI治疗中预防性使用泮托拉唑能有效防止消化道出血的发生。Objective To study the preventive effect of pantoprazole on alimentary tract hemorrhage in patients with acute myocardial infarction（AMI） performed percutaneous coronary artery stent implantation（PCI）.Methods Eighty-seven patients with AMI performed PCI were divided into observation group and control group.Forty-two patients in control group were treated with conventional therapy,based on this,forty-five patients in observation group were treated with pantoprazole.The success rate of PCI,complication,case fatality rate and alimentary tract hemorrhage within seven days in two groups were observed during hospitalization.Results The rate of alimentary tract hemorrhage in observation group and control group was 4.4% and 21.4% respectively,the rate of alimentary tract hemorrhage in observation group was significantly lower than that in control group（P〈0.05）.Conclusion Pantoprazole can effectively prevent alimentary tract hemorrhage in patients with AMI performed PCI.

关 键 词：急性心肌梗死 经皮冠状动脉支架植入术 泮托拉唑 消化道出血 

分 类 号：R542.22[医药卫生—心血管疾病]