预防艾滋病母婴传播规范用药的影响因素分析  

Influencial Factors of Standard Medication in Preventing Mother-to-child Transmission of HIV

作　　者：李爱杰[1] 汪永忠[2] 

机构地区：[1]云南省妇幼保健院,云南昆明650051 [2]昆明市疾病预防控制中心,云南昆明650228

出　　处：《中国皮肤性病学杂志》2012年第6期516-517,533,共3页The Chinese Journal of Dermatovenereology

基　　金：国家十一五重大科技专项(2009ZX10004-902)

摘　　要：目的探讨预防艾滋病母婴传播抗病毒治疗规范用药的影响因素,为制定规范用药的措施提供依据。方法分析云南省5个艾滋病高、中流行县(市、区)158例接受母婴传播阻断服务孕产妇的规范用药状况,采用病例对照研究方法调查规范用药的影响因素,其中病例组53例,对照组105例。结果艾滋病母婴传播阻断抗病毒治疗规范用药的主要影响因素为产次(OR=3.469,95%CI:1.417～8.497)、少数民族(OR=2.808,95%CI:1.100～7.170)、未知情选择(OR=3.723,95%CI:1.123～12.344)、丈夫态度(OR=0.373,95%CI:0.167～0.832)。结论艾滋病母婴传播阻断抗病毒治疗规范用药受多种因素影响,有必要针对主要影响因素制定规范用药措施。Objective To understand influencial factors of standard medication of antiretroviral therapy with preventing mother-to-child transmission of HIV（PMTCT） and contribute to future design of interventional measures to increase standard medication in PMTCT.Methods Analying 158 case records about antiretroviral therapy of PMTCT in 5 HIV high or mid epidemic counties（city and district） in Yunnan from January 2006 to March 2008 to understand the status of canonical medication.Case-control study was used to exam the influencial factors of standard medication for antiretroviral therapy in PMTCT,in which,case group was 53,control group was 105.Results The main correlations with the standard medication level of HIV positive pregnant women and their infants were as follows：times of delivery（OR=3.469,95%CI：1.417～8.497）,minorities（OR=2.828,95%CI：1.100～7.170）,not informed choice（OR=3.723,95%CI：1.03～12.344）,the support of husband（OR=0.353,95%CI：0.167～0.832）.Conclusion Standard medication is associated with multiple factors.It is necessary to make some steps to improve standard medication of antiretroviral therapy in PMTCT.

关 键 词：获得性免疫缺陷综合征 孕产妇 抗病毒治疗 规范 

分 类 号：R512.91[医药卫生—内科学]