SiO_2包覆的羟基磷灰石纳米粒子的制备与性能研究  

Research on preparation and property of silica-coated HAP particles

作　　者：王洪新[1] 陈晓明[2] 王友法[1] 程东霁[3] 

机构地区：[1]武汉理工大学生物材料与工程研究中心,湖北武汉430070 [2]广州医学院生物医学工程系,广东广州510182 [3]皖西学院机械与电子工程学院,安徽六安237012

出　　处：《功能材料》2012年第11期1434-1437,1442,共5页Journal of Functional Materials

基　　金：广东省科技攻关资助项目(2010B031100002)

摘　　要：采用正硅酸乙酯(TEOS)水解法在羟基磷灰石粉体表面包覆SiO2进行表面改性,并通过扫描电镜(SEM)、透射电镜(TEM)、X射线衍射(XRD)、红外(FT-IR)、zeta电位和沉降实验等对样品的晶体结构、颗粒形貌进行了表征,结果表明涂层厚度约为3nm,包覆后的纳米粒子在水溶液中的胶体稳定性提高了5倍,SiO2在羟基磷灰石表面的吸附符合异质凝结机制。Nanophase hydroxyapatite（HAP） particles were coated with silica via the hydrolysis of tetraethyl orthosilicate（TEOS）.The nanocomposite particles were characterized by transmission electron spectroscopy（TEM）,scaning electronmicroscopy（SEM）,X-ray diffraction（XRD）,Fourier transform infrared（FT-IR） spectroscopy,sedimentation timeand zeta potential（ζ） studies.A sequential changes in infrared spectral features characteristic of HAP was accompanied by an increase in features characteristic of silica as revealed by FT-IR.The silica coating enhanced the colloidal stability of HAP in aqueous suspensions.This behavior can be explained based on a heterocoagulation coating mechanism in which silica clusters adsorb onto the HAP particle surface.

关 键 词：羟基磷灰石 表面修饰 正硅酸乙酯 纳米粒子 

分 类 号：TN383[电子电信—物理电子学]