玉屏风散颉颃镉致鸡肝脏氧化损伤作用的研究  

The Rivary Study of the Yupingfeng Power to the Cadmium Toxicosis on the Liver in Chicken

作　　者：费东亮[1] 肖银霞[1] 陈强[1] 苏禹刚[1] 王立成[1] 

机构地区：[1]辽宁医学院畜牧兽医学院,辽宁锦州121001

出　　处：《中国农学通报》2012年第14期96-98,共3页Chinese Agricultural Science Bulletin

基　　金：辽宁省教育厅资助项目"抗亚慢性镉中毒药物的筛选及作用机制研究"(L2010264)

摘　　要：为了研究玉屏风散对镉对鸡肝脏氧化损伤的颉颃作用。将150只30日AA公鸡随机分为3组:对照组(A:饲喂基础日粮)、加镉组(B:组饲喂基础日粮+CdCl2150 mg/kg)和玉屏风散加镉组(C:饲喂基础日粮+CdCl2150 mg/kg的基础上每天灌服玉屏风散1 mL),所有动物自由采食,染毒后15、30、45、60天时分别从以上3组中取10只鸡剖杀,用于肝脏组织相关指标的检测。结果表明:随着镉作用时间的延长,试验组的GSH-Px、SOD的活性降低,MDA生成量增加;试验组与对照组差异显著(P<0.05)或极显著(P<0.01),C组各项指标数据介于A组和B组之间。因此,玉屏风散可减轻镉中毒对机体抗氧化功能的影响,对镉中毒有颉颃作用。To study the rivaty of the Yupingfeng Power to the Cadmium toxicosis on the liver in chicken,and the 150 30-day cocks were divided into 3 groups： the control group（A： feeding on a basal diet）,the Cadmium group（B： feeding on a basal diet ＋ 150 CdCl2150 mg/kg）,the Yupingfeng power and the Cadmium group（C： feeding on a basal diet＋150 CdCl2150 mg/kg＋1 mL the Yupingfeng power days）,and all of them were allowed to feed on freely.The 10 cock of every group were killed after 15,30,45,60 days,then the targets were detected in livers tissue.The results showed that as time of the Cadmium toxicosis prolonging,the activity of GSH-Px and SOD reduced in B group and C group,and the MDA production increased;The difference between the test group and the control group was significant（P0.05） or significantly increased（P0.01）,and each index of C group was between A group and B group.The conclusion was that the Yupingfeng powder could reduced the Cadmium toxicosis effect,and rival the Cadmium toxicosis.

关 键 词：鸡 镉中毒 肝脏 玉屏风散 颉颃 

分 类 号：S856.9[农业科学—临床兽医学]