Detection of TNT by a molecularly imprinted polymer film-based surface plasmon resonance sensor  

作　　者：BAO Han WEI TianXin LI XiuLi ZHAO Zhe CUI He ZHANG Peng 

机构地区：[1]Key Laboratory of Cluster Science of Ministry of Education Beijing Institute of Technology,Beijing 100081,China [2]China Ship Research Development Academy,Beijing 100192,China [3]Chinese Naval Academy of Armament,Beijing 100073,China

出　　处：《Chinese Science Bulletin》2012年第17期2102-2105,共4页

基　　金：supported by the National Natural Science Foundation of China (20771015);the Programme of Introducing Talents of Discipline to Universities (B07012)

摘　　要：A surface plasmon resonance(SPR) sensor using a molecularly imprinted polymer(MIP) film as a recognition element for detection of 2,4,6-trinitrotoluene(TNT) was developed.The TNT-imprinted polymer film was prepared by thermo initiated polymerization on the bare Au surface of an SPR sensor chip.Template TNT molecules were quickly removed with an organic solution of acetonitrile/acetic acid(9:1,v/v),causing a shift of 0.7° in SPR angle.The limit of detection for TNT was demonstrated to be as low as 1×10-8 mol/L.In the concentration range of 1×10-8-1×10-5 mol/L,the change of SPR angle was linear with the negative logarithm of TNT concentration,Selectivity studies showed that the SPR sensor had no response to TNT analogues 2,4,5-trinitrotoluene and 1,3,5-trinitrohexahydro-1,3,5-triazine at a concentration of 1×10-4 mol/L.The results suggest that the SPR sensor combined with a MIP film has the advantages of high sensitivity and selectivity,and long-term stability toward the analyte TNT.A surface plasmon resonance （SPR） sensor using a molecularly imprinted polymer （M1P） film as a recognition element for detec- tion of 2,4,6-trinitrotoluene （TNT） was developed. The TNT-imprinted polymer film was prepared by thermo initiated polymerization on the bare Au surface of an SPR sensor chip. Template TNT molecules were quickly removed with an organic solution of acetonitrile/acetic acid （9 ： 1, v/v）, causing a shift of 0.7° in SPR angle. The limit of detection for TNT was demonstrated to be as low as 1 × 10^-8 mol/L. In the concentration range of 1 × 10^-8- 1 × 10^-5 mol/L, the change of S PR angle was linear with the negative logarithm of TNT concentration. Selectivity studies showed that the SPR sensor had no response to TNT analogues 2,4,5-trinitrotoluene and 1,3,5-trinitrohexahydro-l,3,5-triazine at a concentration of 1 × 10^-4 mol/L. The results suggest that the SPR sensor combined with a MIP film has the advantages of high sensitivity and selectivity, and long-term stability toward the analyte TNT.

关 键 词：分子印迹聚合物膜 表面等离子体共振 TNT炸药 传感器检测 聚合物薄膜 SPR传感器 三硝基甲苯 浓度范围 

分 类 号：TQ560.7[化学工程—炸药化工] TP212.2[自动化与计算机技术—检测技术与自动化装置]