核酸分子“光开关”的研究进展  

Progress of the Nucleic Acid Molecular “Light Switch”

作　　者：凌连生[1] 何治柯[1] 吴风武[1] 罗庆尧[1] 曾云鹗[1] 

机构地区：[1]武汉大学化学系,武汉430072

出　　处：《高等学校化学学报》2000年第4期527-531,共5页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金 !(批准号 :2 960 5 0 0 1)

摘　　要：综述了核酸分子“光开关”的发展及最新动态 ,阐述了它在核酸分子识别分析中的应用 ,并提出了研究核酸分子“光开关”The progress of nucleic acid molecular “Light Switch” and DNA was reviewed in this paper, which is obtained with ultraviolet absorption spectrum, fluoremetry, NMR, T m and linear dicroism(LD), etc . The mechanism of fluorescence enhancement of molecular “Light Switch” by DNA and the charge transfer reaction between Ru(Ⅱ) and Rh(Ⅱ) are reported. It also describes the application of nucleic acid molecular “Light Switch” in sequence analysis, quantitative analysis of DNA, determination of c cm and detection of solvent polarity. The possible development of the nucleic acid molecular “Light Switch” is addressed. [WT5HZ]

关 键 词：核酸分子识别 电荷转移反应 核酸分子光开关 

分 类 号：Q523.03[生物学—生物化学]