α-氧代烯酮环二硫代缩酮化学——α-氧代烯酮环二硫代缩酮与烯丙基Grignard试剂加成物的甲醚化反应  

Oxoketene Cyclic Dithioacetal Chemistry——The Etherifying Reaction on the Adducts of Aliphatic α-Oxoketene Cyclic Dithioacetals with Allyl Magnesium Bromide

作　　者：朱再明[1] 梅泽民[1] 王寅[1] 刘群[2] 杨智蕴[2] 

机构地区：[1]辽宁师范大学化学系,大连116029 [2]东北师范大学化学系,长春130024

出　　处：《合成化学》2000年第2期164-166,共3页Chinese Journal of Synthetic Chemistry

摘　　要：在BF3 ·Et2 O催化下 ,脂肪族α 氧代烯酮环二硫代缩酮与烯丙基Grignard试剂 1 ,2 加成物 ,同亲核试剂甲醇反应得甲醚化物 ,产物经元素分析、IR ,1HNMR确证。Aliphatic α oxoketene cyclic dithioacetals(1) were reacted with allyl magnesium bromide to afford the 1,2 addition products 2. The adducts 2 were etherified by methanol to afford the corresponding methyl ethers 3 in the presence of boron trifluoride etherate as a catalyst. This process provides a new method for the protection of the acid sensitive hydroxyl troup in 2 under mild condition.

关 键 词：环二硫代缩酮 烯丙基 GRIGNARD试剂 甲醚化反应 

分 类 号：O626[理学—有机化学]