醋酸氯己定与甲酚红的荷移反应及应用  

Application of Charge Transfer Reaction Between Chlorhexidine Acetate and Cresol Red

作　　者：赵桂芝[1] 李华侃[1] 陈连山[1] 

机构地区：[1]锦州医学院,锦州121001

出　　处：《分析化学》2000年第3期365-367,共3页Chinese Journal of Analytical Chemistry

摘　　要：研究并确定了醋酸氯已定与甲酚红的荷移反应条件。在乙醇-丙酮介质中形成1：1型络合物，其λmax=455nm，醋酸氯已定浓度在0～80mg/L范围内呈线性关系；表观摩尔吸光系数为1．08×104L·mol-1·cm-1；桑德尔灵敏度是0．0345μg·cm-2；相对标准偏差小于1％（n＝8），回收率符合要求。The charge transfer reaction between chlorhexidine acetate and cresol red in alcohol-acetone solution was studied specbophotometrically. The apparent molar absorptivity is 1 .08×104L·mol-1·cmat 455 nm. The Beer's law was obeyed in the range of 0～80 mg/L of chlothexidine acetate. The composition of complex is 1: 1. The proposed was applied to the determination of chlothexidine aretate with satisfactory results.

关 键 词：醋酸氯己安 甲酚红 分光光度法 药物分析 

分 类 号：O657.3[理学—分析化学]