白癜风细胞免疫研究新进展  

Advances in the Research of Vitiligo Cellular Immunity

作　　者：吴成[1] 周晓鸿[1] 

机构地区：[1]昆明医学院第二附属医院皮肤科,昆明650033

出　　处：《医学综述》2012年第9期1338-1340,共3页Medical Recapitulate

基　　金：云南省联合专项基金(2009CD174)

摘　　要：白癜风是一种常见的色素脱失性皮肤病,其病因复杂,发病机制尚未完全明确。近年来的研究表明,细胞免疫与白癜风的发病发展关系密切。异常分布的CD4+T细胞、CD8+T细胞、朗格汉斯细胞、自然杀伤细胞、黑素特异性T细胞及其他免疫细胞及细胞因子在白癜风的发病与黑素细胞损伤和凋亡过程中发挥着重要的作用。Vitiligo is a common skin disorder characterized by the skin devoid of melanocytes.The etiology of vitiligo is complex and the pathogenesis has not been well understood.In resent years many intensive studies show that cellular immunity is closely related with vitiligo pathogenesis.Researches have found that CD4 ＋T cells,CD8 ＋T cells,Langerhans cells,nature killer cells,melanocyte-specific T cells,immunity cells and cytokines play important roles in the pathogenesis and melanocyte injuries and apoptosis.

关 键 词：白癜风 黑素细胞 细胞免疫 

分 类 号：R758.41[医药卫生—皮肤病学与性病学]