农村高血压人群空腹血糖水平与体质指数及腰围的关系研究  

Correlation between body mass index or waist and fasting blood glucose of hypertensive population in rural communities

作　　者：王伟业[1] 燕燕[1] 陶源[1] 许敏锐[1] 秦献辉[1] 邢厚恂 唐根富[1] 臧桐华[1] 徐欣[3] 徐希平[1] 

机构地区：[1]安徽医科大学生物医学研究所,安徽合肥230032 [2]连云港市现代心血管病防治研究中心,江苏连云港222006 [3]深圳大学生物医药研究所,广东深圳518060

出　　处：《中华疾病控制杂志》2012年第5期375-377,共3页Chinese Journal of Disease Control & Prevention

基　　金：国家科技部重大新药创制专项(2012ZX09101105);国家科技型中小企业创新基金(07C26224421831)

摘　　要：目的了解农村中老年高血压人群空腹血糖(fasting blood glucose,FBG)水平的分布及其与体质指数(body mass index,BMI)、腰围(waist circumference,WC)的关系。方法在连云港市随机抽取20个乡镇,筛查出45～75岁原发性高血压患者,对其进行问卷调查、体格检查和生化检测。结果共纳入研究对象19 123人,平均FBG为(5.82±1.90)mmol/L,男女FBG水平的差异有统计学意义(P<0.001);空腹血糖异常率及糖尿病患病率分别为14.05%和13.50%;在调整混杂因素后,多元Logistic回归分析结果显示,随着腰围增大,男女性空腹血糖异常的风险(男性:OR=1.012,95%CI:1.001～1.024;女性:OR=1.020,95%CI:1.011～1.030)和糖尿病患病风险(男性:OR=1.036,95%CI:1.023～1.050;女性:OR=1.034,95%CI:1.025～1.044)均增加;而BMI与血糖水平的相关性并不明显。结论农村高血压人群空腹血糖水平较高,且腰围与血糖水平相关,提示腹型肥胖者易发生空腹血糖异常或糖尿病,应作为重点预防对象。Objective To investigate the distribution of fasting blood glucose（FBG） of hypertensive population in rural communities,and to find the correlation between body mass index（BMI） or waist circumference（WC） and FBG.Methods Hypertensive population aged 45-75 years old in 20 towns which were randomly selected from Lianyungang were recruited.Data were collected by questionnaire interview,physical examination and biochemical test.Results A total of 19 123 participants were included in the study,their FBG level was（5.82±1.90） mmol/L,level of female was higher than male（P〈0.001）.The prevalence of impaired fasting glucose（IFG） and diabetes mellitus were 14.05% and 13.50% respectively.The multivariate Logistic regression analysis showed that the risk of IFG（male： OR=1.012,95%CI： 1.001-1.024;female： OR=1.020,95%CI： 1.011-1.030） and diabetes mellitus（male： OR=1.036,95%CI： 1.023-1.050;female： OR=1.034,95%CI： 1.025-1.044） increased with WC grow in male and female,but the influence of BMI was not significant.Conclusions FBG level is high in rural hypertensive population,and significant positive correlation exist between WC and FBG,it shows that abdominal obesity people have higher risk of IFG and diabetes.

关 键 词：农村人口 高血压 危险因素 流行病学研究 

分 类 号：R181.1[医药卫生—流行病学] R544.1[医药卫生—公共卫生与预防医学]