屋尘螨变应原制剂治疗变应性鼻炎的临床疗效观察  

Efficacy evaluation of specific immunotherapy with standardized house dust mite allergen preparation for allergic rhinitis

作　　者：周洁[1,2] 何源萍[1,2] 曾旭东[1,2] 李泽文[1,2] 潘芳名[1,2] 陈应超[1,2] 李兆龙[1,2] 

机构地区：[1]华中科技大学同济医学院附属孝感医院 [2]孝感市中心医院耳鼻咽喉科,湖北孝感432000

出　　处：《临床耳鼻咽喉头颈外科杂志》2012年第11期487-489,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:评价屋尘螨变应原制剂治疗变应性鼻炎(AR)的临床疗效。方法:采用病例自身对照的方法,通过比较55例AR患者在接受2年的屋尘螨变应原制剂特异性免疫治疗前后的症状、体征积分,观察该制剂的临床疗效。结果:55例患者在完成特异性免疫治疗后的症状、体征积分较治疗前均明显减少,差异具有统计学意义(P<0.01)。结论:屋尘螨变应原制剂是治疗尘螨引起的AR的一种有效治疗方法。Objective：To evaluate the efficacy of specific immunotherapy（SIT） with standardized house dust mite allergen preparation for allergic rhinitis（AR）.Method：Fifty-five patients with allergic rhinitis caused by house dust mites were selected in this self-control study.Clinical efficacy was evaluated by symptom and sign score after two years of specific immunotherapy and compared with pre-treatment scores.Result：After completing the study,a clinically significant reduction in symptom and sign score in these patients was noted,compared with that of pre-treatment.And the difference was statistically significant（P0.01）.Conclusion：Standardized house dust mite allergen preparation is an effective treatment in patients suffering from allergic rhinitis due to house dust mites.

关 键 词：鼻炎 变应性 常年性 屋尘螨 变应原制剂 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]