老年人社区获得性肺炎住院患者抗菌药物合理应用调查分析  

The Old Community-acquired Pneumonia Patients in Hospital Antimicrobial the Reasonable Application of the Survey Analysis

作　　者：黄小茜[1] 李丽[1] 

机构地区：[1]肇庆市第一人民医院药剂科,广东肇庆526021

出　　处：《中国医药指南》2012年第12期15-17,共3页Guide of China Medicine

摘　　要：目的通过对老年人社区获得性肺炎患者抗菌药物应用情况的调查分析,从全方位了解此类患者抗菌药物应用情况,关注并促进老年人用药安全,为医院药品管理及临床合理用药提供参考。方法采取回顾性调查方法,查阅2010年6月至2011年7月共153例在65岁以上的社区获得性肺炎住院患者的病案资料,对患者抗菌药物的使用情况及用药相关的情况进行调查分析。结果在治疗过程中,全部患者均接受静脉滴注抗菌药物治疗,抗菌药物使用率达100%。所涉及的抗菌药物有5大类17种,应用频次最多的是β-内酰胺类。DDDS排序前10位的药物DUI大于1.1的占5种,显示抗菌药物用量过大;联合用药以二联为主;抗菌药物平均使用天数10.86d;住院平均天数11.35d。结论由于病原学诊断阳性率不高,CAP患者抗菌药物的选择主要还是经验治疗。所调查的153例病例中,抗菌药物的选择基本合理、有效。但在药物的用量方面没有充分考虑老年人的生理特点而进行适当的减量,在抗菌药物序贯治疗方面,以及治疗过程中的监测方面也有待提高。提高老年人的用药安全,有赖于临床各科室之间的合作和努力。Objective To old people through community-acquired pneumonia patients antimicrobial application situation analysis of the investigation,in all these patients understand antimicrobial application situation,attention and promote the old safe drug use and for the hospital drugs management and clinical rational drug use for reference.Methods Retrospective survey method to check from June 2010 to July 2011 a total of 153 patients in 65 years of community-acquired pneumonia of hospitalized patients with medical record material,the patients the usage of antibiotics and drug related was investigated and analyzed.Results In the course of treatment,all patients will receive antimicrobial treatment intravenous injection,antimicrobial drug utilization rate of 100%.Involves the antibacterial drugs have 5 types 17 kinds of application is the largest frequency B-gave n-phenylimide class.DDDS ordering 10 drugs more than 1.1 for DUI five,antimicrobial usage show too much;Combination with two league for the Lord;Average days antimicrobial use 10.86 days;An average of 11.35 days in hospital days..Conclusion As the etiology of positive diagnosis is not high,CAP antimicrobial choice patients with major treatment or experience.The survey of 153 cases,the choice of antimicrobial basic reasonable and effective.But in the dosage of the drug not fully consider the old people＇s physical characteristics and the appropriate reducing antimicrobial treatment in sequential aspects,and in the course of treatment is a need to further improve the monitoring.Improve the elderly＇s drug safety,depend on the cooperation between clinical all hospitals and hard work.

关 键 词：老年人 社区获得性肺炎 单病种 抗菌药物 合理用药 

分 类 号：R563.1[医药卫生—呼吸系统] R969.3[医药卫生—内科学]