慢性病毒性肝炎肝郁血瘀证失眠患者失眠特征及加味血府逐瘀汤的干预作用  

Insomnia Features of Chronic Viral Hepatitis with Insomnia(Syndrome of Liver Stagnation and Blood Stasis) and Intervention of Modified Xuefu Zhuyu Decoction

作　　者：张压西[1] 叶之华[2] 

机构地区：[1]武汉市中医医院,湖北武汉430014 [2]湖北中医药大学,湖北武汉430065

出　　处：《中国中医药信息杂志》2012年第5期10-12,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家自然科学基金(30973687)

摘　　要：目的观察慢性病毒性肝炎肝郁血瘀证失眠患者的失眠特征及加味血府逐瘀汤的临床疗效。方法选取符合标准的慢性病毒性肝炎肝郁血瘀证失眠患者60例,随机分为中药组、对照组各30例,分别用加味血府逐瘀汤和艾司唑仑治疗30 d,观察失眠特征及治疗后失眠特征、中医证候单项症状改善情况。结果 2组均能改善睡眠,中药组疗效优于对照组,差异有统计学意义(P<0.01);治疗后中药组失眠特征和中医证候积分与治疗前比较明显下降,差异有统计学意义(P<0.05或P<0.01)。结论慢性病毒性肝炎肝郁血瘀证的失眠特征以多梦夜醒、早醒及头昏健忘为主,加味血府逐瘀汤能明显改善患者的失眠特征及临床症状,提高患者睡眠质量。Objective To observe the insomnia features of chronic viral hepatitis patients with insomnia（syndrome of liver stagnation and blood stasis） and clinical efficacy of modified Xuefu Zhuyu Decoction.Methods Sixty cases of standards-compliant patients were randomly assigned to two groups,30 cases in the traditional Chinese medicine group treated with modified Xuefu Zhuyu Decoction,and 30 cases in the control group treated with estazolam for 30 d.The insomnia feature,TCM syndrome and clinical efficiency of the two groups were observed.Results Sleep status was improved in two groups.Efficacy of traditional Chinese medicine group,compared with the control group,the difference was statistically significant（P0.01）.There were significant differences in insomnia features and TCM syndrome between the two groups（P0.05 or P0.01）.Conclusion Insomnia features of chronic viral hepatitis are mainly dreaminess,night waking,early weaking,dizziness and forgetfulness.Modified Xuefu Zhuyu Decoction can significantly improve insomnia features and clinical symptoms of patients,thus improve the quality of sleep.

关 键 词：慢性病毒性肝炎 肝郁血瘀证 失眠特征 加味血府逐瘀汤 

分 类 号：R259.126[医药卫生—中西医结合]