应力负荷下兔肩袖急性断裂重建后腱-骨修复过程中的超声检测  

Ultrasonic testing of tendon-bone repair in rabbits with postreconstructive acute ruptured rotator cuff under stress

作　　者：李森[1] 靳安民[2] 张辉[2] 闵少雄[2] 王清[1] 

机构地区：[1]泸州医学院附属医院脊柱外科,四川省泸州市646000 [2]南方医科大学附属珠江医院骨科中心,广东省广州市510282

出　　处：《中国组织工程研究》2012年第20期3630-3633,共4页Chinese Journal of Tissue Engineering Research

基　　金：泸州医学院自然科学基金(泸医院[2010]108号-64)~~

摘　　要：背景:已有研究证明,应力刺激对肩袖腱-骨损伤后的修复起到促进作用,但超声动态检测其修复过程的相关研究还较少。目的:应用超声检测应力刺激促进兔肩袖急性断裂重建后腱-骨修复的过程。方法:选取成年雄性新西兰白兔,建立应力负荷下兔肩袖急性断裂重建后腱-骨修复动物模型,随机分为2组:应力负荷组与非应力负荷组。应力负荷组术后第2周应用兔肩关节被动活动控制装置进行训练;非应力负荷组正常笼养。结果与结论:术后2周,关节超声检查显示两组冈上肌腱止点处回声仍连续性中断,应力负荷组炎性渗出物信号较明显。术后4周,两组冈上肌腱止点重建处均出现线性连续回声,应力负荷组稍显明显。术后6周,两组冈上肌腱腱-骨之间回声仍不连续,应力负荷组腱性连续性中断回声带明显减小。术后8周,两组冈上肌腱腱-骨之间回声仍不完全连续,腱-骨结构连接组织回声区较前宽大。结果显示一定的应力刺激在兔肩袖急性断裂术后腱-骨修复过程中起到积极促进作用,且超声可以相对无创、准确地显示兔肩袖腱-骨修复的动态过程。BACKGROUND： Pervious studies have showed stress can promote tendon-bone repair, but studies related to ultrasonic testing during tendon-bone repair are few. OBJECTIVE： To study the changes in ultrasonic testing of tendon-bone in rabbits with postreconstructive acute ruptured rotator cuff under stress. METHODS： Adult male New Zealand white rabbits were selected for establishing animal models of tendon-bone repair with postreconstructive acute ruptured rotator cuff under stress, and then were randomly divided into two groups： stress group and non-stress group. Rabbits in the stress group were trained at 2 weeks after operation. Non-stress group was with caging and free. RESULTS AND CONCLUSION： At 2 weeks after operation, the echoes at the site of the rabbit supraspinatus tendon-bone were still discontinuous and the signals of inflammatory exudation appeared more evidently than before in the two groups. At 4 weeks after operation, the linear continuous echoes appeared at the site of the rabbit supraspinatus tendon-bone in two groups, which showed more obvious in the stress group than that in the non-stress group. At 6 weeks after operation, the echoes at the site of the rabbit supraspinatus tendon-bone were still discontinuous in two groups, the areas of discontinuous echoes in stress group tendon significantly reduced. At 8 weeks after operation, the echoes at the site of the rabbit supraspinatus tendon-bone were still discontinuous in two groups, the areas of echoes of the tissues combined tendon and bone is more spacious than before. A certain degree of stress stimulation plays an active role in the repairing of postoperative actue ruptured rabbit rotator cuff tendon-bone and ultrasonic testing can detect the dynamic role of tendon-bone repair with non-invasive and accurate.

关 键 词：应力负荷 重建术后:腱骨修复 超声 兔 

分 类 号：R318[医药卫生—生物医学工程]