雷米芬太尼在剖宫产术中对母儿影响的临床观察  

Effect of intravenous remifentanil used in cesarean section on the parturient and neonate

作　　者：郜红艳[1] 蔡恒宇[1] 

机构地区：[1]沈阳市妇婴医院麻醉科,110011

出　　处：《中国现代药物应用》2012年第10期4-5,共2页Chinese Journal of Modern Drug Application

摘　　要：目的探讨雷米芬太尼复合丙泊酚用于剖宫产术的可行性和安全性。方法选择24例足月行剖宫产的产妇,ASAI或II级,随机分成两组:一般全麻组(P组)和雷米芬太尼-丙泊酚全麻组(RP组),每组各12例。观察新生儿的脐动脉血气、Apgar评分和产妇的血流动力学变化,脑电双频指数(BlS)和术中知晓等指标。结果两组新生儿的Apgar评分、脐动脉血气相比差异无统计学意义(P>0.05);产妇血流动力学变化,RP组与基础值相比差异无统计学意义(P>0.05),P组插管后与基础值比较差异有统计学意义(P<0.05),两组气管插管后相比差异有统计学意义(P<0.05)。两组产妇BlS值比较差异无统计学意义(P>0.05),术后随访无术中知晓。结论雷米芬太尼复合丙泊酚用于剖宫产全麻能有效维持母体血流动力学的稳定,对新生儿无明显影响。Objective To observe the effect of remifentanil administered intravenously combined with propfol for cesarean section on theparturient and neonate. Methods 24 healthy parturients scheduled for cesarean section were randomly divided into two groups. Group RP induced with remifentanil and propfol, Group P induced with propfol, observe the change of hemodynamics parameter, umbilical arterial （UA） blood samples were obtained at delivery for blood gas analysis. Apgar scores were assessed at 1st, 5th and 10th minute. Side effects of parturients and newborns were observed. Results There were significant difference of hemodynamic parameter in the both groups and no difference of umbilical arterial cord blood gas analysis and Apgar scores be- tween the groups. Conclusion Remi-fentanil used in the general anesthesia may achieve the stability of the hemo-dynamic and the recovery is quickly, and it is no significant adverse effects on mothers and newborns.

关 键 词：剖宫产手术 雷米芬太尼 丙泊酚 新生儿 APGAR评分 

分 类 号：R614[医药卫生—麻醉学]