苏州市0-14岁儿童支气管哮喘相关因素分析  

Risk factors of asthma among children aged 0 - 14 in Suzhou city

作　　者：朱灿红[1] 刘继贤[1] 赵显虹[1] 

机构地区：[1]苏州大学附属儿童医院呼吸科,215003

出　　处：《中华预防医学杂志》2012年第5期456-459,共4页Chinese Journal of Preventive Medicine

摘　　要：目的 了解苏州地区儿童支气管哮喘（简称哮喘）发病的影响因素。方法 在2010年9月至2011年4月，采用全国过敏哮喘协作组统一制定的0-14岁儿童哮喘调查表、0-14岁非哮喘儿童调查表，在苏州市平江区进行哮喘流行病学调查，在已复查出的540例哮喘患儿中抽取271例作为病例组，同时按1：1配对方法选择与病例组年龄相近、性别相同、民族相同的271例非哮喘儿童为对照组，采用X^检验、logistic回归等进行数据分析。结果 调查对象均为汉族。病例组271例患儿中，男性165例、女性106例，对照组男女人数均与病例组相同。病例组年龄为（7.5±2.3）岁，对照组为（7.8±2.9）岁，年龄差异无统计学意义（P＞0.05）。家庭过敏史（OR=10.624,95％CI：6.294-18.623）、儿童湿疹史（OR=1.403,95％CI：8.627-29.632）、过敏性鼻炎史（OR=6.871,95％CI：7.658-31.871）、出生前后有家人吸烟（OR=3.323,95％CI：3.541-11.634）、家中霉斑（OR=1.837,95％CI：1.531-4.926）为危险因素、母乳喂养（OR=0.513,95％CI：0.418-0.914）为保护因素。结论 家庭过敏史、儿童湿疹史、过敏性鼻炎史、家中霉斑、出生前后有无家人吸烟是哮喘的危险因素，母乳喂养为哮喘的保护因素。Objective This study aimed to investigate risk influencing faetors of asthma for ehihh＇en in Suzhou City, China. Methods A survey of asthma was conducted on ehildren aged 0 - 14 with or without asthma from Septemher 2010 to April 2011 in Pingjiang district of Suzhou eity. A total of 271 ehildren diagnosed with asthma were considered as a ease group, and 271 non-asthmatic children with the same age, sex and living region tormed the control group. Risk factors were analyzed with X^2 test and logistie regression analysis. Results All children were Han. The ease group was composed of 165 boys and 106 girls, so was the ease group. The average age was （ 7.5± 2.3 ） years fur the ease group and （ 7.8 ± 2. 9 ） years for the control group, whieh did not showed any significant differenee（ P 〉 0. 05 ）. Family history of allergy （ OR = 10. 624,95 % CI：6. 294 - 18. 623 ） , history of ehildren＇ s eczema （ OR = 4. 403, 95 % CI ： 8. 627 - 29. 632 ） , history of allergic rhinitis （ OR = 6. 871 , 95% CI： 7. 658 - 31. 871 ） , passive smoking whetl baby was bonl （ OR = 3. 323,95% CI：3. 541 - 11. 634 ） , mold contamination（ OR = 1. 837,95% CI： l. 531 - 4. 926 ） were the risk factors, and breast-feeding （ OR = 0. 513, 95% CI： 0.418 - 0.914 ） was the protective taetor. Conclusion Family histol7 of allergy, history of children＇s eczema, history of allergic rhinitis, passive smoking, and old eontamination are the risk factors, and breast-feeding is the protective factor.

关 键 词：哮喘 儿童 危险因素 病例对照研究 

分 类 号：R725.6[医药卫生—儿科]