护理干预对白血病化疗后深部真菌感染效果的临床研究  

Clinical effect of nursing intervention on deep fungal infections in leukemia patients after chemotherapy

作　　者：滕玉琴[1] 施鹏飞[1] 

机构地区：[1]杭州市第一人民医院血液科,浙江杭州310006

出　　处：《中华医院感染学杂志》2012年第11期2339-2341,共3页Chinese Journal of Nosocomiology

摘　　要：目的观察护理干预对白血病患者化疗后发生深部真菌感染的临床效果,探讨其临床价值,以期为临床工作提供理论支持。方法收集在医院确诊的90例化疗后发生深部真菌感染的患者,留取口腔、痰、尿、血液等,进行真菌培养;依患者的入院顺序分为观察组(45例)与对照组(45例),对照组应用常规护理,观察组应用特定的护理干预,观察两组干预后的临床效果及对患者焦虑的影响。结果 90例感染患者中,最常见的真菌为白色假丝酵母菌,占50.00%,其次为热带假丝酵母菌,占27.78%;观察组护理干预后的临床缓解率为86.67%,明显高于对照组的53.33%,差异有统计学意义(χ2=11.9048,P<0.05);观察组护理干预后焦虑评分为(36.67±3.41)分,明显低于对照组的(39.70±4.21)分,差异有统计学意义(t=6.53,P<0.05)。结论白血病化疗后深部真菌感染主要致病菌为白色假丝酵母菌、热带假丝酵母菌和曲霉菌属;特定的护理干预能有效缓解病情,减轻焦虑情况,对治疗有重要促进作用。OBJECTIVE To investigate the clinical effect and value of nursing interventions on deep fungal infections in leukemia patients after chemotherapy,so as to provide theoretical basis for clinical practice.METHODS A total of 90 leukemia patients with deep fungal infections after chemotherapy were selected.Oral samples,sputum,urine and blood were preserved for fungal culture.According to the order of admission,the patients were divided into observation group（45 cases） and control（45 cases） group.The observation group received special nursing intervention,and the control group received normal nursing.The clinical effect and the anxiety scores after the interventions were compared.RESULTS Among the 90 cases with infection,the most common pathogen was Candida albicans（50.00%）,followed by C.tropicalis（27.78%）.The clinical remission rate of the observation group（86.67%） after nursing intervention was significantly higher than control group（53.33%）（χ2=11.9048,P〈0.05）.The scores of anxiety were significantly lower in the observation group（36.67±3.41） than control group（39.70±4.21）（t=6.53,P〈0.05）.CONCLUSION The common pathogens causing deep fungal infections in leukemia patients after chemotherapy are C.albicans,C.tropicalis and Aspergillus.Special nursing intervention can effectively alleviate the disease condition,relieve anxiety and have important promoting effects on treatment.

关 键 词：白血病 化疗 深部真菌感染 护理 焦虑 

分 类 号：R181.32[医药卫生—流行病学]