核素肺通气灌注显像与64排CT肺动脉造影诊断恶性肿瘤患者肺栓塞的对比研究  

Pulmonary ventilation/perfusion imaging and 64-slice CT pulmonary angiography in diagnosis of pulmonary embolism in patients with malignant tumor: a correlation study

作　　者：李丽娟[1] 冯贵生[1] 张胜潮[1] 张广伟[1] 曹金红[1] 任福林[1] 

机构地区：[1]山西省人民医院核医学科,太原030012

出　　处：《中国药物与临床》2012年第5期568-570,共3页Chinese Remedies & Clinics

基　　金：山西省人民医院青年科研项目(200868)

摘　　要：目的比较肺通气灌注显像(V/Q)与64排CT肺动脉造影(CTPA)在诊断恶性肿瘤患者肺栓塞(PE)方面的临床应用价值。方法回顾性分析50例临床疑诊肺栓塞恶性肿瘤患者的临床资料、实验室检查及影像学检查,比较V/Q显像与CTPA对该类患者的诊断效能。结果 36例患者最终诊断为肺栓塞,V/Q显像诊断的灵敏度、特异性、准确性分别为91.7%,85.7%及90.0%;CTPA诊断的灵敏度、特异性、准确性分别为88.9%,92.9%及90.0%;两者定性诊断结果差异无统计学意义(P>0.05),符合率为80.0%。结论肺通气灌注显像与64排CT肺动脉造影在定性诊断恶性肿瘤患者肺栓塞方面各具优势,应相互结合用于该疾病的早期诊断,治疗方案选择及疗效评价。Objective To compare the clinical application value of pulmonary ventilation/perfusion imaging （V/ Q） and 64-slice CT pulmonary angiography （64-slice CTPA） in diagnosis of pulmonary embolism （PE） in patients with malignant tumor. Methods The clinical datas of 50 malignant tumor patients suspected with PE were retrospectively analyzed and performed laboratory test and imaging examination. Thereafter, the diagnostic efficiency between V/Q imaging and CTPA was then compared. Results Thirty-six patients were finally diagnosed with PE. The sensitivity, specificity and accuracy of V/Q imaging was 91.7%, 85.7%, and 90.0%, respectively. On other hand, the sensitivity, specificity and accuracy of CTPA was 88.9%, 92.9% and 90.0%, respectively. No difference was found in the etiologic diagnosis between V/Q and CTPA. Conclusion V/Q imaging and 64-slice CAPT had their own advantages in diagnosis of PE in patients with malignant tumor. Thus, they should be combined in early diagnosis of PE, selection of treatment scheme and evaluation of efficacy.

关 键 词：肺栓塞 放射性核素显像 体层摄影术 X线计算机 

分 类 号：R563.5[医药卫生—呼吸系统]