一种多巴胺分子印迹的电化学传感器  

A Molecularly Imprinted Electrochemical Sensor of Dopamine

作　　者：邢宪荣[1] 廉文静[1] 刘素[2] 

机构地区：[1]济南大学化学化工学院,山东济南250022 [2]济南大学资源与环境学院,山东济南250022

出　　处：《济南大学学报（自然科学版）》2012年第3期255-259,共5页Journal of University of Jinan(Science and Technology)

基　　金：国家自然科学基金(31101296);山东省自然基金(ZR2010DQ025);山东省高等学校科技计划(J10LB14);济南大学博士基金(XBS1034)

摘　　要：利用分子印迹技术,结合聚苯胺、多壁碳纳米管和金纳米粒子-丝素蛋白复合物构建新型检测多巴胺的分子印迹电化学传感器。分子印迹聚合物以多巴胺为模板,正硅酸乙酯和苯基三乙氧基硅烷为功能单体合成。当pH值为7.0,模板与单体的物质的量比为1∶5时,该传感器的线性范围为5.0×10-8～9×10-6mol/L,检测限(LOD)为1.02×10-8mol/L。重复实验的相对标准偏差为5.4%。A novel sensitive molecularly imprinted electrochemical sensor has been developed for se!ective detection of dopamine by combination of polyaniline, muhiwalled carbon nanotube and gold nanoparticle-silk fibroin composite. The molecularly imprinted pol- ymer （MIP） was synthesized using dopamine as the template molecule ,tetraethyl orthosilieate and triethoxyphenylsilane as the function- al monomers. Under pH = 7.0 and the template-monomer ratio of 1 ： 5, the current response had a linear relationship with the concentra- tion of dopamine in the range of 5.0-10 -s mol/L-9 x 10 -6 mol/L,with a limit of detection 1.02-10 -s mol/L. The relative standard deviation （RSD） of the repeated experiments was 5.4%.

关 键 词：电化学传感器 分子印迹聚合物 聚苯胺 多壁碳纳米管 金纳米粒子-丝素蛋白复合物 多巴胺检测 

分 类 号：O657.1[理学—分析化学]