射频超声技术评价冠心病患者颈动脉弹性的临床研究  

Evaluation of carotid artery elasticity in patients with coronary artery disease by ultrasound radio-frequency data technique

作　　者：王怡[1] 段云友[1] 张莉[1] 袁丽君[1] 许磊[1] 杨一林[1] 曹铁生[1] 

机构地区：[1]第四军医大学唐都医院超声诊断科,西安710038

出　　处：《中华医学超声杂志（电子版）》2012年第5期34-38,共5页Chinese Journal of Medical Ultrasound(Electronic Edition)

摘　　要：目的探讨射频超声血管测量技术在评价冠心病患者颈动脉弹性及其与冠状动脉病变关系中的应用价值。方法选择临床疑似冠心病患者127例为研究对象,根据冠状动脉造影结果分为非冠心病组(A组:对照组)、冠状动脉粥样硬化病变组(B组)、单支病变组(C组)、多支病变组(D组)。对以上4组患者行颈总动脉射频超声检查,记录颈动脉弹性参数,包括血管内中膜厚度(IMT)、脉搏波传导速度(PWV)、动脉管壁的扩张性系数(DC)和顺应性系数(CC)、硬度指数(α)、硬度指数(β),运用统计学方法比较4组间各参数的差异并对其进行相关性分析。结果 A、B、C及D组IMT分别为(586.250±124.12)、(586.567±128.21)、(626.432±124.51)、(691.033±132.01)μm,组间差异有统计学意义(F=3.923,P<0.05),且A、B、C组分别与D组比较,差异有统计学意义(t=2.404、3.171、2.061,P均<0.05);A、B、C及D组PWV分别为(7.561±1.411)、(7.742±1.715)、(9.014±2.339)、(9.420±2.624)m/s,组间差异有统计学意义(F=4.175,P<0.01),且A、B组分别与C组比较,差异有统计学意义(t=1.996、2.343,P均<0.05),且A、B组分别与D组比较(t=2.471、2.917,P均<0.05);A、B、C及D组DC分别为(0.021±0.010)、(0.018±0.009)、(0.015±0.007)、(0.013±0.007)l/kPa,组间差异有统计学意义(F=3.740,P<0.05),且A组与C组比较(t=3.089,P<0.05),且A、B组分别与D组比较(t=2.761、2.416,P均<0.05);A、B、C及D组CC分别为(1.141±0.620)、(0.997±0.522)、(0.749±0.353)、(0.706±0.360)mm2/kPa,组间差异有统计学意义(F=4.512,P<0.01),且A、B组分别与C组比较,差异有统计学意义(t=2.685、2.284,P均<0.05),且A、B组分别与D组比较(t=2.881、2.509,P均<0.05);A、B、C及D组α分别为(4.287±1.620)、(4.870±1.969)、(6.714±3.891)、(7.283±4.102),组间差异有统计学意义(F=4.103,P<0.01),且A、B组分别与C组比较,差异有统计学意义(t=2.183、2.222,P均<0.05),且A、B组分别与D组比较,差异有统计学意义(t=2.607、2.745,PObjective To investigate the value of ultrasound radio-frequency（RF） data technique in assessing carotid artery elasticity and its relationship with the coronary artery pathology in patients with coronary artery disease（CAD）.Methods A total of 127 patients with suspected CAD were enrolled in this study and they were divided into non CAD group（group A：control group）,atherosclerosis group（group B）,single artery involved（group C）and multi-arteries involved（group D）groups according to the severity of coronary arterial stenosis defined by coronary angiography（CAG）.All patients received ultrasound RF-datatechnique examination on the carotid artery.The following elastic parameters：intima-media thickness（IMT）,stiffness parameter（α）,stiffness parameter（β）,pulse wave velocity（PWV）,distention coefficient（DC）,compliance coefficient（CC）were obtained.The correlation of them and the differences among the four groups were analyzed.Results IMT in group A,B,C and D were（586.250±124.12）,（586.567±128.21）,（626.432±124.51）,（691.033±132.01） μm resperitively,There were statistical different among the groups（F=3.923,P0.05）.Compared group A with group B,C and D,there were statistical differences（t=2.404,3.171,2.061,all P0.05）;PWV in group A,B,C and D were（7.561±1.411）,（7.742±1.715）,（9.014±2.339）,（9.420±2.624）m/s,There were statistical differences among the groups（F=4.175,P0.01）.Compared group A,B with group C,there were statistical differences（t=1.996,2.343,all P0.05）.Compared group A,B with group D,there were statistical differences（t=2.471,2.917,all P0.05）;DC in group A,B,C and D were（0.021±0.010）,（0.018±0.009）,（0.015±0.007）,（0.013±0.007）l/kPa,There were statistical difference among the groups（F=3.740,P0.05）,Compared group A with group C,there was statistical differences（t=3.089,P0.05）.Compared group A with group B and D,there were statistical differences（t=2.761,2.416,all P0.05）;CC in gr

关 键 词：超声检查 冠状动脉疾病 颈动脉 弹性 射频技术 

分 类 号：R541.4[医药卫生—心血管疾病] R445.1[医药卫生—内科学]