不同产地白芍HPLC指纹图谱及芍药苷和芍药内酯苷含量的比较研究  

Comparative study of HPLC fingerprints and Paeoniflorin and Albiflorin contents in Paeoniae Radix Alba from different regions

作　　者：朱如彩[1] 蔡萍[1] 李雅[1] 李芳荣[1] 

机构地区：[1]湖南省中医药研究院中药研究所,湖南长沙410013

出　　处：《湖南中医药大学学报》2012年第3期34-37,共4页Journal of Hunan University of Chinese Medicine

基　　金：湖南省科学技术厅科技计划项目(2008SK3090)

摘　　要：目的建立湘白芍、亳白芍与杭白芍HPLC指纹图谱分析方法,并对3种不同产地药材进行主要化学成分的比较。方法采用HPLC对11批白芍样品进行指纹图谱分析,并测定了主要化学成分芍药苷和芍药内酯苷的含量。结果所建立的方法精密度、稳定性和重现性良好;11批白芍样品的指纹图谱有8个共有峰。结论通过建立白芍指纹图谱的定性、芍药苷及芍药内酯苷的定量,为白芍的质量控制提供了更为全面的方法。Objective To establish HPLC fingerprints method and compare the main chemical constituents of Paeoniae Radix Alba from Hunan,Anhui and Zhejiang.Methods The fingerprints of 11 Paeoniae Radix Alba samples from different regions are analyzed by HPLC method.The contents of main chemical constituents such as Paeoniflorin and Albiflorin were analyzed.Results The established method is of good precision,stability and reproducibility.The fingerprints of the 11 samples of Paeoniae Radix Alba share 8 same peaks.Conclusion The established method in this study on fingerprints of Paeoniae radix Alba in qualitatively and content of Paeoniflorin and Albiflorin in quantitatively has provided a more comprehensive means for the quality control of Paeoniae Radix Alba.

关 键 词：HPLC 指纹图谱 白芍 芍药苷 芍药内酯苷 

分 类 号：R284.1[医药卫生—中药学]