抗结核病基因及相关因子的研究进展  

Research progress of anti-tuberculosis genes and their related factors

作　　者：陈元圆[1,2] 马勋[1] 薄新文[2] 黄新[2] 贾文俊[3] 

机构地区：[1]石河子大学动物科技学院,新疆石河子832000 [2]新疆农垦科学院畜牧研究所,新疆石河子832000 [3]石河子大学水利建筑工程学院,新疆石河子832000

出　　处：《黑龙江畜牧兽医》2012年第6期28-30,共3页Heilongjiang Animal Science And veterinary Medicine

基　　金：国家重点实验室开放基金课题家畜疫病病原生物学项目(SKLVEB2009KFKT016)

摘　　要：结核病以其高传染性和高死亡率受到世界各国的普遍关注。尽管,结核病的治疗还是以药物为主,但抗结核病基因Ipr1、SP110以及相关因子的发现,将结核病的治疗与研究推上了一个新的台阶。文章就抗结核基因和相关因子的研究概况以及今后的发展趋势进行综述,旨在为有效控制结核病的发生、发展提供帮助。There is widespread concern about tuberculosis in the countries in the world , which is a highly contagious disease with a high mortal- ity rate. At present , the treatment for tuberculosis still focuses on the drug, but the discoveries of tprl （ Intracellular pathogen resistance 1 ）and Sp110 genes and related factors will push the research and treatment into a new step. This article reviews the current status and development trend of anti - tuberculosis genes and their related factors, in order to provide help for the effective control of the occurrence and development of tuberculosis.

关 键 词：抗结核基因 相关因子 天然抗性巨噬细胞蛋白(NRAMP) Ipr1 Sp110 

分 类 号：S852.618[农业科学—基础兽医学]