高通量与常规血液透析治疗尿毒症60例对比观察  

The clinical comparative study of the effect of uremia treatment between High flux hemodialysis and conventional hemodialysis

作　　者：张志勇[1] 李明旭[1] 马军红[1] 赵君[1] 

机构地区：[1]海军总医院肾内科,北京100048

出　　处：《陕西医学杂志》2012年第5期570-571,584,共3页Shaanxi Medical Journal

摘　　要：目的:探讨高通量与常规血液透析治疗尿毒症的临床疗效及相关机制。方法:选择我院血液透析科尿毒症患者60例,随机分为观察组和对照组,每组30例。分别比较两组患者透析前、后的各项检测值。结果:观察组β2-MG,iPTH大分子物质下降率明显高于对照组(P<0.05);而SCr,BUN、血磷等小分子物质下降率与对照组比较无显著性差异(P>0.05)。结论:采用高通量血液透析治疗尿毒症临床疗效满意,经济方便,不良反应少。Objective： To investigate the high through put and conventional hemodialysis in treatment of uremia in the clinical curative effect and related mechanisms.Methods： a randomly selected from 2009 January to 2011 January admitted to our hospital hemodialysis department in 60 uremic patients,which could be divided into the observation group and the control group,30 cases in each group.Were compared between the two groups patients before dialysis,after the changes of the detected value.Results： the two groups of patients in the observation group comparison,determination of the beta 2-MG,iPTH macromolecular substances decrease rate was significantly higher than the control group,the difference was statistically significant（P 0.05）;while the SCr,BUN,serum phosphorus small molecular substances such as drop rate compared with the control group,the difference was not statistically significant（P 0.05）.Conclusion： using high flux hemodialysis in treatment of uremia clinical curative effect,economy and convenience,fewer adverse reactions,is worth popularizing in dialysis room.

关 键 词：尿毒症/治疗 肾透析 对比研究 @高通量血液透析 

分 类 号：R692.5[医药卫生—泌尿科学]