GC法测定广西产千年健芳樟醇含量  

Determination of Linalool in Homalomona Occulta from Guangxi by GC

作　　者：谢丽莎[1] 蒙田秀[1] 欧阳炜[1] 龚志强[1] 

机构地区：[1]广西中医学院赛恩斯新医药学院,南宁530222

出　　处：《中国药师》2012年第5期607-608,共2页China Pharmacist

基　　金：广西壮族自治区科技攻关项目资助项目(桂科攻编号:0537017-18)

摘　　要：目的:建立气相色谱(GC)法测定广西6个产地千年健药材中芳樟醇含量的方法。方法:样品以乙酸乙酯为溶剂,采用HP-5MS石英毛细管色谱柱(30 m×0.25 mm×0.25μm),初始温度70℃,程序升温上升到250℃,EI离子源,检测器温度300℃,载气流速1.0 ml·min^(-1)。结果:芳樟醇进样浓度在33～330μg·ml^(-1)范围内呈现良好线性关系(r=0.999 5),平均回收率为98.0%,RSD=1.08%。结论:该方法简便,结果准确,可靠,重复性好。广西6个产地千年健药材均达到《中国药典》芳樟醇含量规定项要求。Objective：To determine the linalool content in Homalomona occulta（Lout.） Schott from six different habitats in Guangxi by GC.Method：The samples were dissolved in acetic ether and injected into an HP-5MS capillary column（30 m×0.25 mm×0.25μm） with initial temperature of 70℃followed by temperature programming to 250℃,ion source of EI,detector temperature of 300℃and carrier gas flow rate of 1.0 ml·min^（-1）.Result：The concentration showed a good linear relationship（r =0.999 5） within the range of 33 ~330μg ？ ml^（-1） and the average recovery was 98.0%with RSD of 1.08%.Conclusion：All of the linalool contents meet the requirements of Chinese Pharmacopoeia.The method is simple,accurate,reliable and reproducible.

关 键 词：千年健 气相色谱 芳樟醇 含量测定 

分 类 号：R927.2[医药卫生—药学]