2010年妇产科抗菌药物用药强度分析  

作　　者：苑海[1] 贾苗辉[1] 赵吉强[1] 崔世怡[2] 

机构地区：[1]河北省保定市妇幼保健院药剂科,071000 [2]保定市第三中心医院药剂科

出　　处：《当代医学》2012年第18期150-152,共3页Contemporary Medicine

摘　　要：目的分析妇产科病区住院患者2010年抗菌药物用药强度,为合理使用抗菌药物提供参考依据。方法以限定日剂量(DDD)为单位,以DDD/(100人·d)值计算抗菌药物使用强度,结合出院患者住院病历进行分析。结果妇产科病区住院患者抗菌药物平均用药强度为99.59。青霉素类、青霉素类+酶抑制剂、硝基咪唑类排名AUD前3位;排名AUD前10位的药品为磷霉素钙片、大环内酯类口服制剂、硝基咪唑类、β-内酰胺类抗生素及其酶抑制剂复合制剂。结论该院可能存在抗菌药物用药过度、用药集中、广谱抗菌药物的使用率高等问题,应进一步加强监督管理。Objective To investigate and analyze the use density of antibiotics in-patients in the obstetrics and gynecology ward of our hospital in 2010and provide the evidence of reasonable use in clinic. Methods Taking defined daily dose （DDD） as the unit,the antibacterial use density （AUD） were calculated and carried on the analysis with discharge records. Results Penicillinscompound preparations of penicillins and enzyme inhibitorsnitroimidazoles ranked in the first three places in turn of AUD The drug ranking in the first ten places came from calcium fosfomycin tablets, oral preparation of macrolidesnitroimidazoles-Lactam antibiotics and therr compound preparations with beta-lactamase inhibitors. Conclusion The hospital may exist such problems as overmedicationdense medication and the high use ratio of broad-spectrum antibiotics in usage in the hospital. It is necessary to strengthen administration.

关 键 词：抗菌药物 用药强度 妇产科病区住院患者 用药分析 

分 类 号：R452[医药卫生—治疗学]