残胃病变患者胆汁反流及幽门螺杆菌感染调查分析  

Bile reflux and Helicobacter pylori infections in patients with residual gastropathy

作　　者：俞高峰 

机构地区：[1]永康市第二人民医院消化内科,浙江永康321307

出　　处：《中华医院感染学杂志》2012年第10期2076-2077,共2页Chinese Journal of Nosocomiology

摘　　要：目的调查残胃病变患者胆汁反流及幽门螺杆菌感染情况。方法选取2009年1月-2011年6月于医院进行胃大部切除术后,发生残胃病变的35例患者为研究对象,将其设为观察组,同时选取35例胃大部切除术后,未发生残胃病变的患者为对照组,将两组患者的胆汁反流及幽门螺杆菌感染情况进行统计分析。结果观察组的胆汁反流占51.4%,幽门螺杆菌感染发生率为37.1%,均高于对照组,且观察组毕Ⅱ式幽门螺杆菌占41.7%及胆汁反流占54.2%,发生率高于毕Ⅰ式,手术时间长者发生率高于手术时间短者,残胃病变中残胃癌发生率高于其他疾病,差异均有统计学意义(P<0.05)。结论残胃病变的发生与胆汁反流及幽门螺杆菌感染等有较大的相关性,在胃大部切除术后应给予足够的重视。OBJECTIVE To investigate the condition of bile reflux and Helicobacter pylori infection in patients with gastric stump lesion.METHODS A total of 35 patients with gastric stump lesions after subtotal gastrectomy from Jan 2009 to Jun 2011 in the hospital were chosen as the research objects and set as the observation group,and totally 35 cases without gastric stump lesion after subtotal gastrectomy at the same time were set as the control group,statistical analysis of bile reflux and H.pylori infections in the patients of the two groups was performed.RESULTS The patients with bile reflux in observation group accounted for 51.4%,the incidence of H.pylori infection was 37.1%,both were higher than those in the control group,the incidence of Billroth Ⅱ-type H.pylori infection in the observation group was 41.7%,and the patients with bile reflux accounted for 54.2%,the incidence was higher than that of Billroth Ⅰ-type H.pylori infection,the incidence of the patients with longer operation time was higher than that with the shorter operation time,the incidence of gastric cancer was higher than that of other diseases during the period of residual gastropathy（P〈0.05）,the differences were statistically significant.CONCLUSION The incidence of residual gastropathy has greater correlation with bile reflux and H.pylori infection,which is worthy of the attention after subtotal gastrectomy.

关 键 词：残胃病变 胆汁反流 幽门螺杆菌 感染 调查 

分 类 号：R181.32[医药卫生—流行病学]