高原习服与低氧预适应  

Altitude acclimatization and hypoxic preconditioning

作　　者：陈良恩[1] 安瑞卿[1] 

机构地区：[1]空军航空医学研究所第一研究室,北京100142

出　　处：《国际病理科学与临床杂志》2012年第2期175-179,共5页Journal of International Pathology and Clinical Medicine

摘　　要：高原低氧易导致急性高原反应,高原习服是机体为适应高原低氧环境发生的一系列代偿适应性变化。寻找加快高原习服的有效措施,提高机体高原习服能力,是预防和减轻急性高原反应的最好策略。低氧预适应是指机体经一次或多次短暂、非致死性低氧刺激后,机体获得的对后续更长时间或更严重低氧性损伤的耐受性。低氧预适应作为一种通过内源性保护机制来提高机体缺氧耐力的有效方法,是促进高原习服的重要措施。Altitude hypoxia often results in acute mountain sickness.Altitude acclimatization is a series of adaptive changes for body to deal with a hypoxic environment.The best strategy to prevent or alleviate acute mountain sickness is to search for measures effective in improving acclimation ability and shortening the acclimation time.Hypoxic preconditioning strengthens the organisms innate ability to resist more severe hypoxia（and/or for longer times） after one or more transitory,immortal hypoxic stimulations.As an efficient method for enhancing anoxic tolerance by inducing endogenous protective mechanisms,hypoxic preconditioning is an important measure to promote altitude acclimatization.

关 键 词：高原习服 低氧预适应 急性高原反应 

分 类 号：R594.3[医药卫生—内科学]