兴安白芷的挥发油成分分析  

GC-MS analysis of the chemical components ofvolatile oil from the root of Angelica dahurica

作　　者：赵爱红[1] 杨鑫宝[2] 杨秀伟[1] 陶海燕[1] 于俊林[3] 王文全[2] 

机构地区：[1]北京大学药学院天然药物学系,天然药物及仿生药物国家重点实验室,北京100191 [2]北京中医药大学,北京100102 [3]通化师范学院制药与食品科学系,通化134002

出　　处：《药物分析杂志》2012年第5期763-768,共6页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:研究兴安白芷(Angelica dahurica Benth.et Hook.f.ex Franch.et Sav.的干燥根)挥发油的化学成分,并分析其与祁白芷挥发油成分之间的异同。方法:采用水蒸气蒸馏法提取挥发油,采用毛细管气相色谱-质谱联用技术分析其挥发油成分。结果:从兴安白芷挥发油中检出244个色谱峰,鉴定了76个化合物,占挥发油总量的86.13%。挥发油主要成分为十四烷醇(tetradecanol,19.43%)、α-柠檬烯(α-limonene,15.25%)、3-蒈烯(3-carene,10.94%)、正十二烷醇(1-dodecanol,5.74%)和1R-α-蒎烯(1R-α-pinene,3.85%)。结论:兴安白芷和祁白芷共有成分有38个,占兴安白芷挥发油总量的34.54%,其倍半萜及其衍生物类成分的数目和含量要远远低于祁白芷。Objective：To study the chemical components of volatile oil from the root of Angelica dahurica Benth.et Hook.f.ex Franch.et Sav.（Xing′anbaizhi）and compare the components difference of volatile oil with that of A.dahurica var.dahurica cv.Qibaizhi（Qibaizhi）.Methods：The volatile oil was extracted by water-steam distillation and analyzed by GC-MS with capillary gas chromatographic column.Results：Two hundred forty-four chromatographic peaks were detected,among which 76 compounds have been identified.The contents of them made up 86.13% of the total volatile oil of Xing′anbaizhi.The main components in the volatile oil of Xing′anbaizhi were tetradecanol（19.43%）,α-limonene（15.25%）,3-carene（10.94%）,1-dodecanol（5.74%）and 1R-α-pinene（3.85%）.Conclusion：The two species contained 38 common components,which amounted 34.54% of the total volatile oil of Xing′anbaizhi.The contents of sesquiterpenes and their derivates in Xing′anbaizhi were lower than that of Qibaizhi.

关 键 词：中药 兴安白芷 挥发油 化合物鉴定 成分分析 水蒸气蒸馏法 毛细管气相色谱-质谱联用技术 

分 类 号：R917[医药卫生—药物分析学]