罗库溴铵不同给药方式对腹部手术术后拔管的影响  

The impact of extubation after abdominal surgery for administration of rocuronium in different ways

作　　者：颜娅[1] 闫红[1] 

机构地区：[1]第三军医大学附属大坪医院麻醉科,重庆400042

出　　处：《中国医药导报》2012年第15期106-107,共2页China Medical Herald

摘　　要：目的比较腹部手术中罗库溴铵不同给药方式对术后拔管的影响。方法2010年1月-2011年6月，选取我院全麻下行开腹手术的患者共110例，随机分成罗库溴铵间断给药组（对照组）和持续泵注组（观察组），分别记录神经肌肉阻滞的最大阻滞时间及起效时间、恢复过程，并记录罗库溴铵的用药量。结果在用药后起效时间、肌松维持时间、用药量、平均泵注速率上，两组患者差异有统计学意义（P〈0．05）；停药后观察组的肌松恢复过程明显快于对照组（P〈0．01）。结论持续泵注肌松药罗库溴铵可为腹部手术提供满意的肌松条件，且停药后肌松恢复过程明显缩短是腹部手术“快通道”麻醉的理想用药方式。Objective To compare the impact of postoperative extubation of Abdominal surgery compared rocuronium ad- ministration of different ways. Methods From January 2010 to June 2011, patients selectd under general anesthesia under- going elective surgery 110 patients were raAdomly divided into intermittent administration of rocuronium group （control group） and the continuous infusion group .（observation group）, neuromuscular blockade were recorded time and the maxi- mum block onset time, the recovery process, and record rocuronium dosage. Results In the treatment onset time, muscle Songwei holding time, the dosage, the average pumping rate, the difference between the two groups were statistically signifi- cant （P 〈 0.05）; Observed after discontinuation of neuromuscular recovery group was significantly faster than the control group （P 〈 0.01）. Conclusion Continuous infusion of muscle relaxants rocuronium surgery for abdominal muscle relaxant to provide satisfactory conditions, and neuromuscular recovery after treatment is significantly shorter abdominal surgery fast track the ideal anesthetic drug approach

关 键 词：腹部手术 肌松药 罗库溴铵 给药方式 

分 类 号：R614[医药卫生—麻醉学]