中药益糖康治疗痰热互结型并有糖调节受损的代谢综合征临床研究  

Clinical Research on Yitangkang Treating MS with IGR

作　　者：王莉[1] 石岩[2] 杨宇峰[2] 连捷[2] 郭建彪[2] 张冰冰[2] 姜楠[2] 刘小溪[1] 王宏涛[2] 秦伟锋[2] 冀天威[2] 陈红谨[2] 

机构地区：[1]辽宁中医药大学附属医院,辽宁沈阳110032 [2]辽宁中医药大学,辽宁沈阳110032

出　　处：《辽宁中医杂志》2012年第5期846-848,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家"十一五"科技支撑计划项目(2007BAI20B103)

摘　　要：目的:客观评价中药益糖康对并有糖调节受损(IGR)的代谢综合征(MS)的临床疗效。方法:采用多中心、随机、双盲、平行对照的试验方法,选择符合WHO诊断标准的患者165例,随机分成治疗组(83例)和对照组(82例)。治疗组予综合治疗并口服益糖康,对照组予综合治疗并口服安慰剂。疗程12周。观察治疗前后患者的空腹血糖、餐后2h血糖、糖化血红蛋白、血脂、血压等指标的变化情况。结果:益糖康治疗可显著降低患者的餐后2h血糖、甘油三酯、总胆固醇、体重指数和血压,与对照组比较有显著性差异(P<0.05)。结论:益糖康对痰热互结型并有IGR的MS具有肯定的治疗作用。Objective：To evaluate the clinical effect of Chinese traditional medicine Yitangkang on MS patients with IGR. Methods：The study was conducted by the random two-blind control experience in 165 cases of MS patients with DGR diagnosed according to WHO standard from the perspective of BMI. The cases were randomly divided into 2 groups and were treated with oral liquid Yitangkang（ group 1 ）and oral placebo （group 2）respectively and observed for 12 weeks. The observation indexes included the indexes of PG, blood fat and blood pressure. Result ： Yitangkang could obviously decrease the levels of PG, TG, TC, BMI and blood pressure ,which had significant differences compared with control group （P 〈 0.05 ）. Conclusion： Yitangkang has positive effect on MS of phlegm-heat accumulation syndrome with IGR.

关 键 词：并有IGR的MS 益糖康 临床试验 

分 类 号：R285.6[医药卫生—中药学]