法舒地尔联合奥扎格雷治疗椎基底动脉供血不足的疗效观察  

The curative effect of fasudil and ozagrel in treatment of vertebrobasilar ischemia

作　　者：涂强[1] 林捷 向明清[1] 马兰[1] 成祥林[1] 

机构地区：[1]长江大学医学院附属第一医院,湖北荆州434002 [2]荆州市第三人民医院

出　　处：《现代预防医学》2012年第12期3148-3149,共2页Modern Preventive Medicine

摘　　要：目的观察法舒地尔加奥扎格雷治疗椎基底动脉供血不足(VBI)的疗效。方法应用法舒地尔加奥扎格雷注射液治疗101例老年椎基底动脉供血不足患者,观察其疗效及治疗前后TCD的变化情况。结果法舒地尔加奥扎格雷治疗后VA、BA、PCA血流速度明显提高,治疗前后比较差异有统计学意义(P﹤0.05),治疗总有效率为96.0%。结论法舒地尔加奥扎格雷治疗椎基底动脉供血不足起效快,效果肯定,不良反应少。OBJECTIVE To observe curative effect of fasudil and ozagrel in treatment of vertebrobasilar ischemia. METHODS 101 old patients with vertebrobasilar ischemia were treated with fasudil and ozagrel, and we observed the effect and changes of TCD before and after treatment. RESULTS The VA, BA and PCA blood flow velocity significantly increased in patients treated with fasudil and ozagrel, and there was significant difference before and after treatment （P﹤0.05）. The total effective rate was 96.0%. CONCLUSION The effect of fasudil and ozagrel in treatment of vertebrobasilar ischemia is quickly, effective and few side effect.

关 键 词：椎基底动脉供血不足 TCD 法舒地尔 奥扎格雷 

分 类 号：R541.4[医药卫生—心血管疾病]