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机构地区:[1]上海普陀区中心医院,200062 [2]华东医院,200040
出 处:《首都医药》2012年第10期25-27,共3页Capital Medicine
摘 要:目的总结克罗恩病(CD)的临床特点及内镜诊断价值。方法收集1981年至2011年经内镜诊断的163例CD患者的相关资料,分析其内镜下表现及临床病理特点。结果 1981年~1995年和1996年~2011年两组中,经内镜诊断的CD患者占同期镜检总数的比例从0.43%上升至0.49%。患者男女之比为1.20:1,平均发病年龄42.6岁,发病年龄呈双峰型分布20~39岁及50~59岁;病程大于10年者占79.14%;临床主要表现为腹痛、腹泻、血便,并伴有贫血、发热、消瘦等全身症状;病变部位属小肠型者占42.94%、结肠型者占23.31%、回结肠型者占33.74%。结论 CD的发病率有上升趋势,临床表现多样化,内镜结合临床及病理学检查是目前诊断CD的主要方法。Objective To evaluate theendoscopic and clinical features of Crohn's disease(CD).Methods The data of 163 patients diagnosed as CD in Huadong Hospital from the year of 1981 to 2011 were reviewed.The endoscopic with biopsy and clinical features of CD were analysed.Results In the two groups from 1981 to 1995 and from 1996 to 2011, the proportion of patients diagnosed as CD under colonoscopy was increased from 0.43% to 0.49%.The ratio of male to female was 1.20. The average age was 42.6 years old.The peak age was between 20 to 39 years old and 50 to 59 years old.79.14% of patients had the course of more than 10 years.The typical clinical manifestations of CD were abdominal pain, diarrhea, hematochezia, and anaemia,fever, weight loss.42.94% of patients had small bowel disease, 33.74 % had small and large bowel involvement, and only 23.31% had large bowel alone.Conclusions The incidence of CD was increased.The chief clinical features was diversification. Colonoscopy with biopsy and clinic are considered to be the major means for the diagnosis of CD.
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