腹腔镜去顶术与穿刺术治疗肾囊肿的Meta分析  

Meta-analysis of laparoscopic unroofing versus puncture for renal cyst

作　　者：王磊[1] 刘修恒[1] 匡幼林[1] 汪志顺[1] 肖腾飞[1] 

机构地区：[1]武汉大学人民医院泌尿外科,湖北省武汉市430060

出　　处：《职业与健康》2012年第9期1052-1055,共4页Occupation and Health

摘　　要：目的探讨腹腔镜去顶术与穿刺术治疗肾囊肿的安全性和有效性。方法计算机检索Pub Med、Cochrane、EMbase、CNKI、万方和维普数据库,查找所有比较腹腔镜去顶术和穿刺术治疗肾囊肿的随机对照试验,检索时限均为建库到2011年12月31日,同时手检纳入文献的参考文献,按纳入排除标准由2人独立进行随机临床试验(RCT)的筛选、资料提取和质量评价后,采用RevMan 5.0软件进行Meta分析。结果共纳入9个研究,共702例患者。Meta分析结果显示,在手术时间和并发症方面,腹腔镜去顶术与穿刺术差异均无统计学意义(P>0.05)。与穿刺术相比,腹腔镜去顶术的术后住院时间较长[WMD=-3.40,95%CI(-3.57,-3.23),P<0.01],复发率较低[OR=19.88,95%CI(8.62,45.85),P<0.01],费用较高[SMD=-5.75,95%CI(-7.58,-3.92),P<0.01]。结论腹腔镜去顶术与穿刺术2种术式相比,安全性方面相似,虽然腹腔镜去顶术的费用更高,术后住院时间较长,但复发率低于穿刺术。[Objective] To evaluate the efficacy and safety of laparoscopic unroofing vs puncture for treatment of kidney cyst.[Methods] The literature databases PubMed,Cochrane Library,EMbase,CNKI,WANFANG and VIP were searched for randomized controlled trials（RCTs） about laparoscopic unroofing vs puncture for the treatment of renal cyst.The duration of search was from the date of the database establishment to December 31,2011.After study selection,data extraction,assessment which were undertaken by 2 reviewers independently according to inclusion and exclusion criteria,meta-analyses were performed by using the RevMan 5.0 software.[Results] Nine studies involving 702 patients met the inclusion criteria.The results of meta-analyses showed that there was no statistical difference between laparoscopic unroofing and puncture（P0.05）.Compared with puncture treatment,the patients with laparoscopic unroofing had longer postoperative hospitalization length[WMD=-3.40,95%CI（-3.57,-3.23）,P0.01] ,lower recurrence rate[OR=19.88,95%CI（8.62,45.85）,P0.01] ,but higher cost[SMD=-5.75,95%CI（-7.58,-3.92）,P0.01] .[Conclusion] The current evidence indicated that laparoscopic unroofing is similar to puncture on the treatment safety,although the cost of laparoscopic unroofing is higher and hospitalization length is longer,while the recurrence rate is less than puncture treatment.

关 键 词：腹腔镜去顶术 穿刺术 肾囊肿 META分析 

分 类 号：R692.9[医药卫生—泌尿科学]