心肌肌钙蛋白Ⅰ定性测定对急性心肌梗塞的诊断价值  

QUALITATIVE ANALYSIS OF CARDIAC TROPONIN I FOR DIAGNOSIS OF ACUTE MYOCARDIAL INFARCTION

作　　者：肖文良[1] 赵维江[1] 任启富[1] 戴华[1] 刘芳[1] 赵淑健[1] 王士昌[1] 

机构地区：[1]河北医科大学第三医院心内科,石家庄050051

出　　处：《河北医科大学学报》2000年第2期65-66,共2页Journal of Hebei Medical University

摘　　要：目的观察急性心肌梗塞(AMI)后血中心肌肌钙蛋白Ⅰ(cTnⅠ)的动态变化。方法应用免疫干膜层析技术,连续测定了40例AMI早期(1～8h)入院患者和10例正常人血中cTnⅠ,结果与心肌酶(CK、CKMB)对比。结果AMI时血中cTnⅠ升高时间较早,持续时间更长,且对心肌细胞损伤诊断的准确性、灵敏性和特异性均优于心肌酶,尤其cTnⅠ定性测定方法简单,出结果迅速。ObjectiveTo observe the dynamic variations of cardiac troponin Ⅰ(cTnⅠ) on patients with acute myocardial infarction (AMI).MethodsBy dry film chromatography immunoassy, cTnⅠ in blood was examined on 40 patients with AMI and 10 normal subjects.The results of cTnⅠ were compared with those of creatine kinase (CK) and its isoenzyme CK MB.ResultscTnⅠ rose earlier than CK MB and maintained for a longer time (6-8 days) in blood on AMI.Blood cTnⅠ positivity accurately and specifically indicated the injury of myocardiocytes.The method of cTnⅠ qualitative measurement is accurate and sensitive. cTnⅠ is an excellent marker for the diagnosis of AMI.ConclusionQualitative analysis of cardiac troponin Ⅰ is of important clinical value for diagnosis of AMI.

关 键 词：心肌梗塞 诊断 AMI 心肌肌钙蛋白Ⅰ 

分 类 号：R542.220.4[医药卫生—心血管疾病]