CAG方案治疗骨髓增生异常综合征RAEB的疗效观察  

Curative Effects of CAG in Treating Myelodyplastic Sydrome RAEB

作　　者：刘小兰 黄爱英 陈勇 孙丽萍 

机构地区：[1]江西新余新钢中心医院,江西338001

出　　处：《安徽卫生职业技术学院学报》2012年第2期40-41,共2页Journal of Anhui Health Vocational & Technical College

摘　　要：目的：探讨CAG方案治疗骨髓增生异常综合征—难治性贫血伴原始细胞增多（MDS-RAEB）的疗效。方法：11例患者使用CAG方案：阿糖胞苷（Ara-C）10mg.m-212h-1皮下注射,第1~14d;阿柔比星7mg.m^-2d^-1,静脉滴注,第1-8d,G-CSF200μg.m^-2d^-1,皮下注射,两个疗程后作评定。结果：11例患者中,CR6例,PR3例,NR2例,CR率为54.5%,有效率81.8%,全组未见明显毒副反应。结论：CAG方案治疗MDS疗效肯定,缓解率较高,可作为部分MDS的治疗手段。objective：To explore the curative effects of CAG in treating MDS-RAEB. Method：11 patients were given CAG plan： 1st day to 14th subcutaneous injection of Ara-C 10mg.m^-212h^-1 ; 1st day to 8th day Intravenous infusion of Aclarubicin Aclarubicin 7mg .m^-2d^-1; subcutaneous injection of G-CSF200μg.m^-2d^-1 Appraisal was made after two treatment durations. Result： among the 11 patients, 6 cases CR, 3 cases PR, 2 cases NR, CR rate is 54.5%, efficiency rate is 81.8%, no evident side-effects occurred. Conclusion： CAG plan proves to be positive in treating MDS, with higher relief rate, which can serve as a treatmetn method in MDS.

关 键 词：骨髓增生异常综合征 难治性贫血伴原始细胞增多 CAG方案:阿糖胞苷阿柔比星 粒细胞集落刺激因子 

分 类 号：R681.1[医药卫生—骨科学]