用“B&G System”检测肾小球滤过率的临床对比研究  

作　　者：邱艳娥[1] 吴锡信[1] 

机构地区：[1]南华大学教学医院广东省第二人民医院,510317

出　　处：《中国社区医师（医学专业）》2012年第13期296-296,共1页

基　　金：广东省科技计划资助项目(2003C104038)

摘　　要：目的:探讨数字化智能检测分析系统("B&G System")检测肾小球滤过率(GFR)的临床价值。方法:随机选择肾内科近两年213例患者,按肾功能分为正常组与异常组,分别用"B&G System"、99mTc-DTPA清除率测定GFR(B&G-GFR、Tc-GFR),用Cockcroft-Gault公式估算CCr(CG-CCr),同时采用全自动生化分析仪测定血清肌酐(SCr)、胱抑素C(CysC);所得数据进行相关分析与对比研究。结果:两组B&G-GFR分别与Tc-GFR、CCr均呈显著正相关,与SCr、CysC呈显著负相关(P值均<0.05),B&G-GFR与Tc-GFR无显著性差异(P>0.05)。结论:"B&G System"检测GFR准确、简便、快速、安全、廉价。Objective： To discuss the clinical value of determining glomerular filtration rate （GFR） by the ＂ B＆G System＂. Meth- ods ：213 hospitalized patients were selected randomly, divided into normal group and chronic renal failure group. GFRs were determined by the ＂ B＆G System＂ （ B＆G - GFR） and the clearance rate of 99mTc- DTPA （To - GFR） , and CCr was estimated by Cockcroft - Gault formula. Simultaneously the serum creatinine（SCr） and Cystatin C （Cys C）were determined. All the results were compared, and correlation analysis was done for the data what obtained. Results： B＆G- GFR of both groups was positively correlated with Tc - GFR and CCr. While negatively correlated with SCr and Cys C（ all P〈 0.05）. B＆G - GFR of both groups showed no significant difference with Tc - GFR（ P 〉 0. 05 ）. Conclusion ： Using ＂B＆G System＂ to analsis GFR was an accurate and simple and celerity and safe and cheap method ,and it should apply and popularize clinically.

关 键 词：肾小球滤过率 血清胱抑素C 血清肌酐 临床应用 

分 类 号：R444[医药卫生—诊断学]