麦芽醇对红细胞自氧化损伤的护保作用  

THE ANTIOXIDATIVE ACTION OF MALTOL ON AUTO-OXIDATION OF ERYTHROCYTES

作　　者：冯立明[1] 潘华珍[1] 张之南[1] 

机构地区：[1]中国协和医科大学,北京100730

出　　处：《中国药理学通报》1990年第1期26-29,共4页Chinese Pharmacological Bulletin

基　　金：国家自然科学基金

摘　　要：红细胞在温育过程中发生自氧化损伤:氧合血红蛋白减少,高铁血红蛋白增多,超氧阴离子自由基增加,脂褐质升高,膜收缩蛋白及带3蛋白减少,带4.5及血红蛋白增多,汉氏小体含量升高,红细胞破溶。麦芽醇系红参中水溶性小分子有效成分,有抗氧化损伤,保护红细胞的作用。The effect of maltol to prevent erythrocyte from auto-oxidation is presented. When erythrocytes were incubated at 37 ℃ for 24 h in vitro, oxyhemoglobin was decreased, methemoglobin, superoxide free radical, lipofuscin and Heinz's body were increased as well as membrane proteins were changed. These reactions could be inhibited by maltol.

关 键 词：麦芽醇 红细胞 自氧化 抗氧化 

分 类 号：R965[医药卫生—药理学]