急性三氯甲烷中毒一例报告  

A Case Report on Acute Trichloromethane Poisoning

作　　者：姚峰[1] 冯玉妹[1] 张雪涛[1] 

机构地区：[1]上海市杨浦区中心医院职业病科,上海200090

出　　处：《环境与职业医学》2012年第5期324-325,共2页Journal of Environmental and Occupational Medicine

摘　　要：[目的]通过对一例职业性急性三氯甲烷中毒病例的报告,以引起相关企业的重视,采取有效防护措施,避免类似事件的发生。同时给医疗机构提供参考,避免误诊。[方法]收治患者后详细询问职业史、病史以及外院诊疗经过,完善实验室检查并邀请消化科会诊,同时调查劳动条件,分析病因,集体讨论综合分析后得出诊断。[结果]患者诊断为三氯甲烷引起的急性轻度中毒性肝病,经对症治疗后痊愈出院,半年及1年随访肝功能均正常。[结论]三氯甲烷可导致肝脏损害。企业主对三氯甲烷的毒性认识不足,未采取有效防护措施是导致此次事件发生的重要原因。[ Objective ] To report a case of acute occupational trichloromethane poisoning, to alert relevant enterprises to similar episodes and to provide reference for avoiding misdiagnosis. [ Methods ] The patient received relevant examination after careful inquiry of medical history including previous visiting and treatment in other institutions. Simultaneously field study was performed for comprehensively understanding the cause of diseasel [ Results ] The patient was diagnosed acute mild toxic hepatitis due to occupational exposure to trichloromethane. After removal from further exposure and symptomatic treatment, the patient was fully recovered. Two clinic follow-ups respectively after half a year and one year showed restored liver function. [ Conclusion ] Trichloromethane can lead to liver damage. In this case, the employers＇ tack of knowledge on the toxicity of trichloromethane failed them to take effective protective measures and finally resulted in occupational poisoning.

关 键 词：三氯甲烷 中毒 肝病 

分 类 号：R135.1[医药卫生—劳动卫生]