阳江原生态红树林土壤放线菌Streptomyces sp.strain V65的次级代谢产物  

Metabolites of the Marine Actinomycetes Streptomycessp. Strain V65 from the Soil Sample from Yangjiang Intact Mangrove

作　　者：向玲丽[1] 梁碧怡[2] 朱成波[1] 王军[1] 刘岚[3] 林永成[3] 

机构地区：[1]中山大学药学院,广东广州510006 [2]佛山市中医院,广东佛山528000 [3]中山大学化学与化学工程学院,广东广州510275

出　　处：《中山大学学报（自然科学版）》2012年第3期143-146,共4页Acta Scientiarum Naturalium Universitatis Sunyatseni

基　　金：国家863计划(海洋生物专题)资助项目(2007AA09Z414)

摘　　要：一株分自阳江原生态红树植物老鼠簕根部土壤的放线菌Streptomyces.strain V65在高氏Ⅰ号培养基中可产生丰富的红色素。采用硅胶柱色谱、反相硅胶柱色谱、LH-20凝胶柱色谱等技术对其菌体和培养液的提取物进行分离,初步得到2个红色素和1个酰胺类化合物;它们的结构通过核磁共振波谱技术及质谱技术鉴定,分别为:Undecylprodigiosin(Ⅰ)Metacycloprodigiosin(Ⅱ)和SW-B(Ⅲ)((2E,4E)-2,4,6-trimethyldeca-2,4-di-enamide)。这是首次关于阳江原生态红树林海洋放线菌Streptomyces.strain V65次级代谢产物研究的报道。The marine actinomycete Streptomyces sp.V65,isolated from the soil sample under Acanthus ilicifolius from Yangjiang intact mangrove,metabolized some red pigments in Gause’s medium（Ⅰ）.Undecylprodigiosin（Ⅰ） and metacycloprodigiosin（Ⅱ） with SW-B（Ⅲ）（（2E,4E）-2,4,6-trimethyldeca-2,4-dienamide）were isolated from its mycelia and fermentation using silica gel column chromatography,RP-18 silica gel column chromatography and Sephadex LH-20 column chromatography.Their structures were characterized by NMR spectroscopy and Mass analysis.The metabolites of the marine actinomycetes Streptomyces sp.strain V65 from Yangjiang intact mangrove were first investigated.

关 键 词：阳江原生态红树林 海洋放线菌 次级代谢产物 

分 类 号：O629.5[理学—有机化学]