Synthesis of pillar[7]arene  

作　　者：Yu Chen Hong Qi Tao Yu Hui Kou Herbert Meier Jian Long Fu De Rong Cao 

机构地区：[1]School of Chemistry and Chemical Engineering,State Key Laboratory of Luminescent Materials and Devices,South China University of Technology,Guangzhou 510641,China [2]Institute of Organic Chemistry,University of Mainz,Duesbergweg 10-14,55099 Mainz,Germany

出　　处：《Chinese Chemical Letters》2012年第5期509-511,共3页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos20872038 and 21072064)

摘　　要：The first synthesis of pillar[7]arene is reported with two methods.Method A：the FeCl_3-catalyzed condensation reaction of 1,4- dimethoxybenzene（1） with paraformaldehyde in CHCl_3 gave dimethoxypillar[7]arene（3）.Method B：the p-toluenesulfonic acid catalyzed condensation reaction of 2,5-bis（benzyloxymethyl）-1,4-dimethoxybenzene（2） in CH_2Cl_2 gave compound 3.Demethylation of 3 with BBr_3 gave pillar[7]arene（4）.The pillar[7]arene might be a perspective macrocyclic host in host-guest chemistry.The first synthesis of pillar[7]arene is reported with two methods.Method A：the FeCl_3-catalyzed condensation reaction of 1,4- dimethoxybenzene（1） with paraformaldehyde in CHCl_3 gave dimethoxypillar[7]arene（3）.Method B：the p-toluenesulfonic acid catalyzed condensation reaction of 2,5-bis（benzyloxymethyl）-1,4-dimethoxybenzene（2） in CH_2Cl_2 gave compound 3.Demethylation of 3 with BBr_3 gave pillar[7]arene（4）.The pillar[7]arene might be a perspective macrocyclic host in host-guest chemistry.

关 键 词：Pillar[n]arenes arene Host-guest chemistry Condensation reaction Iron（Ⅲ） chloride 

分 类 号：TQ241[化学工程—有机化工] TD355.3[矿业工程—矿井建设]