树鼩腺病毒(Ⅰ和Ⅱ型)的生物学性状、抗原关系和血清抗体的研究  

Biological Characteristics, Relationship between Antigen and Serology of Tupaial Adenoviruses(Type Ⅰ and Ⅱ)

作　　者：吴小闲[1] 唐恩华 张新生 徐维明[2] 谢广珍 文喻玲[2] 刘名英[2] 肖慧芳 涂新明[1] 蒋虹[1] 施慧君[1] 曲丽荣 

机构地区：[1]中国医学科学院实验动物研究所 [2]中国医学科学院医学生物学研究所 [3]昆明军区后勤部军事医学研究所

出　　处：《中国医学科学院学报》1990年第2期153-156,共4页Acta Academiae Medicinae Sinicae

摘　　要：树鼩已作为实验动物用于各方面的研究.70年代以来,国内、外先后报道的树鼩病毒有疱疹病毒(THV)、腺病毒(TAV.1个血清型)、逆转录病毒、副流感病毒和弹状病毒等.1981～1985年从云南野生树鼩的咽拭子、肾细胞培养物和粪便分离出2个血清型的TAV(TAV-Ⅰ和TAV-Ⅱ),对其生物学特性、抗原关系和血清抗体进行研究报道如下.The strains of adenovirus were isolated from pharyngeal swabs, kidney cell cultares and stool of tupaias. They were identified by a series tests of biological characteristics and electron microscopy studies. 10 strains of tupaia adenoviruses (TAV) may be divided into two serum types: termed TAV-I and TAV-Ⅱ. There was no cross-reactivity of neutralization antibody between TAV-I and TAV-Ⅱ, except a slight cross-reactivity in the complement fixation test. TAV-I could hemagglutinate R.B.C. of rat, mouse, human tO' type, and tupaia itself, but TAV-Ⅱ, couldn't. The positive rate of TAV-Ⅰ and TAV-Ⅱ antibodies in blood was more than 50% in natural tupaia population, suggesting of TAV infecting latently in wild tupaia colony.

关 键 词：树QU 腺病毒 抗原 血清抗体 

分 类 号：R373.9[医药卫生—病原生物学]