碳酸氢钠减轻儿童应用红霉素胃肠道反应疗效观察  

Observation of sodium bicarbonate injection's effect on alleviating the gastrointestinal reaction of children injected with lactose acid injection Erythromycin

作　　者：丁俊东 

机构地区：[1]珠海市平沙医院,广东珠海519055

出　　处：《基层医学论坛》2012年第13期1657-1658,共2页The Medical Forum

摘　　要：目的观察应用5%碳酸氢钠注射液减轻小儿应用注射用乳糖酸红霉素(Erythromycin)时所致胃肠道不良反应的疗效。方法将126例临床应用注射用乳糖酸红霉素静脉输液的病例随机分为2组,A组63例,输入注射用乳糖酸红霉素,在输液的配制中加入5%碳酸氢钠注射液;B组63例,在输入注射用乳糖酸红霉素时未加入5%碳酸氢钠注射液,观察2组胃肠道不良反应。结果 A组病例输注注射用乳糖酸红霉素的阳性率明显低于B组,差异有统计学意义(P<0.01)。结论在患儿应用注射用乳糖酸红霉素治疗时加入5%碳酸氢钠注射液,可以大大减少该药物在儿科临床应用的明显胃肠道反应,为合理阶梯应用该抗生素提供了可行性方案,值得临床推广应用。Objective To observe the 5% sodium bicarbonate injection reduce gastrointestinal adverse reactions induced by lactose acid erythromycin in infantile injection.Methods Choosing 126 cases of clinical application with lactose acid injection erythromycin intravenous infusion.The cases were randomly divided into two groups.Group A： 63 cases,transfuse erythromycin injection,adding 5% sodium bicarbonate in the infusion,Group B： 63 cases,transfuse erythromycin without sodium bicarbonate.Observing the gastrointestinal adverse.Results The positive rate of group A was significantly lower than group B,the difference was statistically significant（P 0.01）.Conclusion Children in the application of erythromycin bicarbonate for injection adding 5% sodium bicarbonate can greatly reduce the drugs of significant gastrointestinal reactions,it is worthy of clinical application.

关 键 词：注射用乳糖酸红霉素(Erythrom ycin) 抗炎治疗 胃肠道反应 5%碳酸氢钠注射液 

分 类 号：R725.1[医药卫生—儿科]