复发性抑郁障碍发病机制及与肝郁关系探讨  

Study on the relationship between Stagnation of Liver-QI and pathogenesis of recurrent depressive disorder

作　　者：李涛[1] 赵阳[1] 汪卫东[1] 洪兰[1] 林颖娜[1] 王芳[1] 闫雪[1] 

机构地区：[1]中国中医科学院广安门医院,北京100053

出　　处：《中医药导报》2012年第5期4-7,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家科技支撑计划"心理疾患防治研究与示范-中国传统医学对心理疾患的防治研究"(2009BAI77B09);中国中医科学院广安门医院所级课题"中医心理疗法治疗抑郁症的脑机制研究"(2009S214)

摘　　要：抑郁症初发与复发的机理有所不同,以往研究提示抑郁症的病理环路在长期病程中可能会有所调试,呈现动态改变,但目前无法清楚了解其初次发作期、缓解期及复发期的神经生化结构改变情况。中医肝郁证与心理应激有关,通过应激诱发抑郁状态可以很好地模拟情志异常引发肝郁证的过程。Pathogeny of first depression is different with its recurrence.Past studies on depressive disorder suggest that its pathological loop may adjust, and present dynamic changes during long-term disease course. However, we still could not fully un- destand its nerval changes of biochemistry structure during first onset period, paracmasis, and recurrence, stagnation of liver-QI is relation with psychological stress. Depression relapse was constructed by stress to imitate the form of stagnation of liver-QI.

关 键 词：抑郁症 机制 肝郁 

分 类 号：R256.4[医药卫生—中医内科学]